Synthesis and Properties of 1,3-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: IV.<sup>1</sup> 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-3-(fluoro, chlorophenyl)ureas

D. Pitushkin; V. Burmistrov; G. Butov

Статья

Synthesis and Properties of 1,3-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: IV.<sup>1</sup> 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-3-(fluoro, chlorophenyl)ureas

D. Pitushkin, V. Burmistrov, G. Butov,

2020

https://doi.org/10.1134/S1070428020080023

Abstract: The reaction of bicyclo[2.2.1]hept-5-en-2-yl isocyanate with fluoro- andchloro-substituted anilines was used to synthesize in a yield of 25–68% a seriesof 1,3-disubstituted ureas containing a lipophilic group in their structure. Thesynthesized ureas are promising as inhibitors of RNA virus replication and humansoluble epoxide hydrolase.

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1. Version of Record от 2020-08-01

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Об авторах

D. Pitushkin
Volgograd State Technical University, Volzhsky Polytechnic Institute, Volgograd State Technical University
V. Burmistrov
Volgograd State Technical University, Volzhsky Polytechnic Institute, Volgograd State Technical University
G. Butov
Volgograd State Technical University, Volzhsky Polytechnic Institute, Volgograd State Technical University

Название журнала

Russian Journal of Organic Chemistry

Том

Выпуск

Страницы

1336-1346

Финансирующая организация

Russian Science Foundation

Номер гранта

19-73-10002

Тип документа

journal article

Тип лицензии Creative Commons

CC BY

Правовой статус документа

Свободная лицензия

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scopus

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Статья

Synthesis and Properties of 1,3-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: IV.<sup>1</sup> 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-3-(fluoro, chlorophenyl)ureas

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