In the modern conditions of global competition, when the implementation of financial and economic activities by industrial enterprises of real sectors of the economy is impossible without possessing unique key competencies that give undeniable advantages over competitors, not only new forms of doing business lead, which undoubtedly appeared during the general global coronavirus pandemic, COVID-19, when most enterprises were forced to switch to a remote mode of work of labor collectives, and consumption has largely shifted to the e-commerce format, but also the ability to optimize work with the existing resource base, which can be fully attributed to obtained results of scientific and technical activities (RSTA), which are inherently unique and limited resource for external participants in business processes. This paper is aimed at researching project management tools that allow the management of high-tech companies that create and work with RSTA to discover new opportunities provided by a new project management tool: economic mechanism of RSTA decomposition. The article examines modern management methods based on the available resource potential. The methodological aspects of the research are based on solving the multi-criteria problem of project management, covering the practical area of research activities carried out by high-tech companies. © Published under licence by IOP Publishing Ltd.