Статья

Sers‐based colloidal aptasensors for quantitative determination of influenza virus

D. Gribanyov, G. Zhdanov, A. Olenin, G. Lisichkin, A. Gambaryan, V. Kukushkin, E. Zavyalova,
2021

Development of sensitive techniques for rapid detection of viruses is on a high demand. Surface‐enhanced Raman spectroscopy (SERS) is an appropriate tool for new techniques due to its high sensitivity. DNA aptamers are short structured oligonucleotides that can provide specificity for SERS biosensors. Existing SERS‐based aptasensors for rapid virus detection had several disad-vantages. Some of them lacked possibility of quantitative determination, while others had sophisti-cated and expensive implementation. In this paper, we provide a new approach that combines rapid specific detection and the possibility of quantitative determination of viruses using the example of influenza A virus. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • D. Gribanyov
    Institute of Solid State Physics of Russian Academy of Science, Chernogolovka, 142432, Russian Federation
  • G. Zhdanov
    Chemistry Department, Lomonosov Moscow State University, Moscow, 119991, Russian Federation
  • A. Olenin
    Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products RAS, Moscow, 108819, Russian Federation
  • G. Lisichkin
  • A. Gambaryan
  • V. Kukushkin
  • E. Zavyalova
Название журнала
  • International Journal of Molecular Sciences
Том
  • 22
Выпуск
  • 4
Страницы
  • 1-13
Ключевые слова
  • aptamer; buffer; Influenza virus hemagglutinin; inorganic salt; silver nanoparticle; amnion fluid; animal cell; Article; colloid; crystal structure; erythrocyte; Influenza A virus (H5N1); Influenza B virus; Influenza virus; nonhuman; photon correlation spectroscopy; quantitative analysis; surface enhanced Raman spectroscopy; virus detection; virus hemagglutination; virus load; virus particle
Издатель
  • MDPI AG
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus