COVID-19.рф: ИНФОРМАЦИЯ ПРОТИВ ПАНДЕМИИ

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Статья

SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2.

E. Zavyalova, O. Ambartsumyan, G. Zhdanov, D. Gribanyov, V. Gushchin, A. Tkachuk, E. Rudakova, M. Nikiforova, N. Kuznetsova, L. Popova, B. Verdiev, A. Alatyrev, E. Burtseva, A. Ignatieva, A. Iliukhina, I. Dolzhikova, A. Arutyunyan, A. Gambaryan, V. Kukushkin,
2021
https://doi.org/10.3390/nano11061394

During the COVID-19 pandemic, the development of sensitive and rapid techniques for detection of viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool for new techniques due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection are either inapplicable for quantitative determination or have sophisticated and expensive construction and implementation. In this paper, we provide a SERS-aptasensor based on colloidal solutions which combines rapidity and specificity in quantitative determination of SARS-CoV-2 virus, discriminating it from the other respiratory viruses.

Цитирование

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Версии

  • 1. Version of Record от 2021-05-25

Метаданные

Об авторах
  • E. Zavyalova
    Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
  • O. Ambartsumyan
    Department of Microbiology, Virology and Immunology, I.M. Sechenov First Moscow State Medical University, 125009 Moscow, Russia.
  • G. Zhdanov
    Chemistry Department, Lomonosov Moscow State University, 119991 Moscow, Russia.
  • D. Gribanyov
    Institute of Solid State Physics of Russian Academy of Science, 142432 Chernogolovka, Russia.
  • V. Gushchin
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • A. Tkachuk
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • E. Rudakova
    Institute of Physiologically Active Compounds of Russian Academy of Science, 142432 Chernogolovka, Russia.
  • M. Nikiforova
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • N. Kuznetsova
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • L. Popova
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • B. Verdiev
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • A. Alatyrev
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • E. Burtseva
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • A. Ignatieva
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • A. Iliukhina
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • I. Dolzhikova
    National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
  • A. Arutyunyan
    Belozersky Research Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
  • A. Gambaryan
    Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products RAS, 108819 Moscow, Russia.
  • V. Kukushkin
    Institute of Solid State Physics of Russian Academy of Science, 142432 Chernogolovka, Russia.
Название журнала
  • Nanomaterials
Том
  • 11
Выпуск
  • 6
Страницы
  • 1394
Издатель
  • MDPI
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • dimensions
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