Статья

Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021.

S. Jungnick, B. Hobmaier, L. Mautner, M. Hoyos, M. Haase, A. Baiker, H. Lahne, U. Eberle, C. Wimmer, S. Hepner, A. Sprenger, C. Berger, A. Dangel, M. Wildner, B. Liebl, N. Ackermann, A. Sing, V. Fingerle, , , , B. Bartha-Dima, K. Bengs, A. Berger, K. Boll, A. Carl, C. Jürgen, J. Drdlicek, D. Eisenberger, J. Flechsler, L. Gerdes, G. Githure, J. Govindaswamy, C. Hupfer, R. Konrad, G. Lupoli, J. Lutmayr, G. Margos, R. Müller, S. Nickel, M. Okeyo, M. Pavlovic, S. Pecoraro, I. Sahm, M. Schauer, A. Schülein, E. Schürmann, G. Schulze, N. Scuda, S. Singer, T. Stellberger, B. Treis, C. Tuschak, P. Zimmermann, N. Paravinja,
2021

SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were respectively diluted both in DMEM and saliva. Dilutions were analysed with Roche, Siemens, Abbott, nal von minden and RapiGEN RATs. While further studies with appropriate real-life clinical samples are warranted, all RATs detected B.1.1.7 and B.1.351, generally comparable to non-VOC strain.

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  • 1. Version of Record от 2021-04-22

Метаданные

Об авторах
  • S. Jungnick
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany, These authors contributed equally to this work
  • B. Hobmaier
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany, These authors contributed equally to this work
  • L. Mautner
    Unit of molecular biologic analytics and biogenetics, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • M. Hoyos
    Unit of molecular biologic analytics and biogenetics, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • M. Haase
    Unit of molecular biologic analytics and biogenetics, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • A. Baiker
    Unit of molecular biologic analytics and biogenetics, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • H. Lahne
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • U. Eberle
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • C. Wimmer
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • S. Hepner
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • A. Sprenger
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • C. Berger
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • A. Dangel
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • M. Wildner
    Ludwig Maximilians-Universität, Munich, Germany, Bavarian State Institute of Health, Oberschleißheim, Germany
  • B. Liebl
    Ludwig Maximilians-Universität, Munich, Germany, Bavarian State Institute of Health, Oberschleißheim, Germany
  • N. Ackermann
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany
  • A. Sing
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany, Ludwig Maximilians-Universität, Munich, Germany
  • V. Fingerle
    Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany

  • Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany, Members of the Bavarian SARS-CoV-Public Health Laboratory Team are listed below
  • B. Bartha-Dima
  • K. Bengs
  • A. Berger
  • K. Boll
  • A. Carl
  • C. Jürgen
  • J. Drdlicek
  • D. Eisenberger
  • J. Flechsler
  • L. Gerdes
  • G. Githure
  • J. Govindaswamy
  • C. Hupfer
  • R. Konrad
  • G. Lupoli
  • J. Lutmayr
  • G. Margos
  • R. Müller
  • S. Nickel
  • M. Okeyo
  • M. Pavlovic
  • S. Pecoraro
  • I. Sahm
  • M. Schauer
  • A. Schülein
  • E. Schürmann
  • G. Schulze
  • N. Scuda
  • S. Singer
  • T. Stellberger
  • B. Treis
  • C. Tuschak
  • P. Zimmermann
  • N. Paravinja
Название журнала
  • Eurosurveillance
Том
  • 26
Выпуск
  • 16
Издатель
  • European Centre for Disease Control and Prevention (ECDC)
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • dimensions