This article examines the contradictions and the characteristics of clustering and innovative development in the agricultural sector. The author’s approach focused on the development of an integrated clustering model of the Volga Region economic space, considering clusters as the fundamental segments of the agricultural sector. The international experience in coordination of territorial and agricultural cluster development was taken into account, the characteristics of the implementation of the Russian cluster policy are attributed. A set of parameters were collected in order to be able to characterize different approaches to cluster policy, depending on the territorial or sectoral affiliation of the cluster. The general directions of improvement of the cluster policy of the Russian Federation within the framework of the neoclusterization model were taken into consideration.