Статья

Consensus Statement for Pharmacological Management of Coronavirus Disease 2019 (COVID-19): A Pragmatic Approach

J. R, J. Y, N. P, K. R, K. AK, T. AA, B. B, J. BG, J. D, L. J, N. J, P. JLP, Z. K, P. KA, H. M, M. MLNG, K. MA, C. MTV, T. M, M. M, S. M, H. M, R. P, P. Q, M. RK, M. RC, G. R, Y. R, B. S, D. S, R. ST, Y. TY, V. W,
2020

Introduction: In the absence of high-quality evidence for Coronavirus disease-2019 (COVID-19), supportive care is advocated during this pandemic. We aim to develop a consensus statement from global experts for pharmacological management, based on the pathophysiology of COVID-19. Material and Methods: We used a modified Delphi methodology in three steps: 1) Formulation of the steering committee and questionnaire; 2) Delphi methodology and selection of experts; 3) Final meeting of the steering committee and analysis, discussion, preparation, and presentation of captured data. Results: 34 (73·9%) experts accepted the invitation for the study. We conducted two rounds of Delphi and consensus (>70% votes) was achieved on 11 out of 24 statements after the end of round two. Conclusion: This global consensus suggests that “Anti-viral therapy should be administered in the early infection phase of COVID-19 followed by low dose steroid therapy in pulmonary phase. Prophylactic dose anticoagulation should be used in hospitalized, mild to moderate COVID-19 patients. We make no suggestions for the use of immune modulation therapy”.

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Версии

  • 1. Version of Record от 2020-12-22

Метаданные

Об авторах
  • J. R
    Consultant Critical Care, Nayati Healthcare, Mathura, Uttar Pradesh, India
  • J. Y
    Head CCM and Emergency Medicine, Regency Super Specialty Hospital, Lucknow, India
  • N. P
    Specialist and Head Critical Care Medicine, Head -Prevention and Control of Infection, NMC Specialty Hospital, Al Nahda 2, Dubai, UAE
  • K. R
    Assistant Professor of Anesthesiology, Department Of Anesthesia and Critical Care Medicine, Mayo Clinic, USA
  • K. AK
    Associate Professor, Section Head for Research, Department of Anesthesiology, Wake Forest University School of Medicine, Cleveland, OH, USA
  • T. AA
    Consultant, Head of ICU at Security Forces Hospital, Dammam, Saudi Arabia
  • B. B
    Director of the Intensive Care Services, Chair Intensive Care Committee, American Hospital Dubai, UAE
  • J. BG
    Head of Critical Care Department, Reliance Hospital, Navi Mumbai, India
  • J. D
    Associate Director, Institute of Critical Care Medicine, Max Super Specialty Hospital, Saket New Delhi, India
  • L. J
    The University of Queensland, Australia; Scientific Consultant, Nimes University Hospital, University of Montpellier, France
  • N. J
    Department of Anaesthesiology, Intensive Care and Pain Medicine, Tan Tock Seng Hospital, Singapore
  • P. JLP
    Medicina Intensiva, Coordinador Neuro UCIN, Jefe del Servicio de Cuidados Intermedios, Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Perú
  • Z. K
    Prof and Head of Department Neuro Intensive Care Unit, Ruby Hall Clinic, Grant medical Foundation, Pune, India
  • P. KA
    Deputy Director, Head of Regional Vascular Centre, Sklifosovsky Research Institute of Emergency Medicine, Bolshaya Sukharevskaya Square, Russia
  • H. M
    Professor and Head of Department, Critical Care Medicine, Ziauddin University, Karachi, Pakistan
  • M. MLNG
    Department Intensive Care Medicine, University Hospital Brussel (UZB), Brussels, Belgium; Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB), Brussels, Belgium
  • K. MA
    Atkinson Morley Regional Neurosciences Centre, St George’s Hospital, London, UK
  • C. MTV
    Professor, Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
  • T. M
    Associate Professor, Department of Internal Medicine, Medical İntensive Care Unit, Gazi University Faculty of Medicine, Turkey
  • M. M
    Clinical Head Adult Multidisciplinary Intensive Care Unit, Department of Medicine, Divisions of Critical Care and Pulmonology, University of the Witwatersrand, Johannesburg, South Africa
  • S. M
    Professor of Intensive Care Medicine, Director, Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, UK
  • H. M
    Pulmonologist, Medcare Hospital Sharjah and Dubai London Clinic and Hospital, Dubai, UAE
  • R. P
    Consultant Intensive Care Physician, Columbia Asia Hospitals, Bangalore, India
  • P. Q
    Professor and Head Department of Anaesthesia and Intensive Care, Rome, Italy; Member of the Board of the FEDERATION EUROPEEN des MEDICINE, Brussels, Belgium; P. Member of the World Commission on Safety and Quality WFSA, WHO; Visiting Professor, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia, Greece; Visiting Professor, Campus Bio Medico University, Rome, Italy
  • M. RK
    Director, Strategy and COVID-19 Management, Yashoda Super Specialty Hospital, Kaushambi, Ghaziabad, UP, India
  • M. RC
    Honorary Consultant Intensivist & Internist, Ahmedabad, India
  • G. R
    Additional Professor of Anaesthesiology, Critical Care, Pain and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India
  • Y. R
    Senior Consultant Critical Care Medicine, Nayati Healthcare, Mathura, UP, India
  • B. S
    Pulmonologist, NMC Royal Hospital DIP, Dubai, UAE
  • D. S
    Clinical Professor of Medicine, UCLA School of Medicine, USA
  • R. ST
    Assistant Professor, Critical Care Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Y. TY
    Clinical Associate Professor, Attending Anesthesiologist and Intensivist, Department of Anesthesiology, National Taiwan University Hospital (NTUH), Taiwan; Chair, Scientific Committee, Taiwan Society of Emergency & Critical Care Medicine (TSECCM), Taiwan; Vice-Chair, Research Committee and International Affairs, TSECCM, Taiwan; Secretary General, Taiwan Society of Critical Care Medicine (TSCCM), Taiwan
  • V. W
    Hospital Posadas, Buenos Aires, Argentina
Название журнала
  • Asploro Journal of Biomedical and Clinical Case Reports
Том
  • 3
Выпуск
  • 3
Страницы
  • 241-256
Издатель
  • Asploro Open Access Publications
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
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  • dimensions