Статья

Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Infection: A Consensus Statement before Guidelines

Z. Zhai, C. Li, Y. Chen, G. Gerotziafas, Z. Zhang, J. Wan, P. Liu, I. Elalamy, Md, Phd, C. Wang, Md, Phd,
2021

Coronavirus disease 2019 (COVID-19) has caused a global pandemic in just a few months, causing millions infected. Nearly 20% of COVID-19 patients present severe coagulation abnormalities, which may occur in almost all of the severe and critical ill COVID-19 cases. Concomitant venous thromboembolism (VTE), a potential cause of unexplained deaths, has been frequently reported in COVID-19 cases, but its management is still challenging due to the complexity between antithrombotic therapy and coagulation disorders. Based on frontline practical experience and comprehensive literature review, here a panel of experts and physicians from China and Europe developed an evidence and opinion-based consensus on the prophylaxis and management of VTE associated with COVID-19. This statement aims for clinicians treating COVID-19 and provides practical recommendations in detailed situations, for example, how to choose thromboprophylactic measures for patients with diverse severity of disease and bleeding risk, or which kind of anticoagulant should be prescribed. With limited experience on COVID19-associated VTE, this expert consensus statement should be helpful for clinicians worldwide with specific suggestions. © 2020 Georg Thieme Verlag. All rights reserved.

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Версии

  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • Z. Zhai
    Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 2 East Yinghua Road, Chaoyang District, Beijing, 100029, China
  • C. Li
    Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
  • Y. Chen
    National Clinical Research Center for Respiratory Diseases, Beijing, China
  • G. Gerotziafas
    Department of Pulmonary and Critical Care Medicine, Affiliated Hospital of Jianghan University, Wuhan, China
  • Z. Zhang
    Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China
  • J. Wan
    Hematology and Thrombosis Center, Tenon University Hospital, INSERM, UMRS 938, Sorbonne University, Paris, France
  • P. Liu
    Department of Clinical Laboratory, Wuhan Asia Heart Hospital, Wuhan, China
  • I. Elalamy
    Department of Cardiovascular Surgery, China-Japan Friendship Hospital, Beijing, China
  • Md
    Department of Obstetrics and Gynaecology, First I.M. Sechenov Moscow State Medical University, Moscow, Russian Federation
  • Phd
    Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
  • C. Wang
  • Md
  • Phd
Название журнала
  • Thrombosis and Haemostasis
Том
  • 120
Выпуск
  • 6
Страницы
  • 937-948
Ключевые слова
  • argatroban; bivalirudin; creatinine; D dimer; dalteparin; danaparoid; enoxaparin; fibrinogen; fondaparinux; low molecular weight heparin; nadroparin; rivaroxaban; tinzaparin; anticoagulant agent; fibrin degradation product; fibrin fragment D; anticoagulant therapy; antithrombotic activity; bleeding; bleeding risk score; blood transfusion; central venous catheterization; computed tomography pulmonary angiography; computer assisted tomography; coronavirus disease 2019; deep vein thrombosis; Doppler flowmetry; echocardiography; extracorporeal oxygenation; high risk patient; hospitalization; human; hypertension; intermediate risk patient; lung angiography; lung ventilation; practice guideline; preeclampsia; priority journal; prophylaxis; respiratory failure; Review; risk assessment; risk factor; Sequential Organ Failure Assessment Score; thrombosis prevention; venous thromboembolism; Betacoronavirus; bleeding; blood; blood clotting disorder; China; complication; consensus; coronavirus disease 2019; Coronavirus infection; critical illness; epidemiology; Europe; lung embolism; pandemic; register; treatment outcome; vein thrombosis; venous thromboembolism; virus pneumonia; Anticoagulants; Betacoronavirus; Blood Coagulation Disorders; China; Consensus; Coronavirus Infections; Critical Illness; Europe; Fibrin Fibrinogen Degradation Products; Hemorrhage; Humans; Pandemics; Pneumonia, Viral; Pulmonary Embolism; Registries; Risk Assessment; Risk Factors; Treatment Outcome; Venous Thromboembolism; Venous Thrombosis
Издатель
  • Georg Thieme Verlag
Тип документа
  • Review
Источник
  • scopus