COVID-19.рф: ИНФОРМАЦИЯ ПРОТИВ ПАНДЕМИИ

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Статья

Syndrome of increased epithelial permeability in clinical practice. Multidisciplinary national Consensus

V. Simanenkov, I. Maev, O. Tkacheva, S. Alekseenko, D. Andreev, D. Bordin, T. Vlasov, N. Vorobyeva, V. Grinevich, I. Gubonina, M. Drobizhev, N. Efremov, A. Karateev, Y. Kotovskaya, I. Kravchuk, G. Krivoborodov, E. Kulchavenya, A. Lila, M. Mayevskaya, E. Poluektova, T. Popkova, O. Sablin, O. Solovyeva, A. Suvorov, G. Tarasova, D. Trukhan, A. Fedotova,
2021
https://doi.org/10.15829/1728-8800-2021-2758

The purpose of the first multidisciplinary Consensus: to comprehensively analyze the pathophysiological, clinical, and pharmacotherapeutic aspects of the syndrome of increased epithelial permeability (SPEP) as one of the basic mechanisms of the development of human pathology. The Consensus presents the structure of the three main levels of cytoprotection: preepithelial, epithelial and subepithelial, and the structure of intercellular tight contacts in epithelial tissues and endothelium is considered in detail. The clinical sections of the Consensus are devoted to the role of SPEP in diseases of the digestive system, cardio-cardiovascular and other visceral systems. A separate section summarizes the materials illustrating the significant role of SPEP in mental disorders and diseases of the nervous system. A separate chapter of the Consensus is devoted to cytoprotective therapy in SPEP. Cytoprotective effects of such proton pump inhibitor as rabeprazole, bismuth preparations and probiotics have been shown. Special attention is paid to the clinical and pharmacological specialties of the cytoprotector of rebamipide. Clinical the effectiveness of rebamipide shown as in functional, so in organic lesions of the digestive system. Its anti-cancer preventive effects are of practical importance.

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Версии

  • 1. Version of Record от 2021-01-01

Метаданные

Об авторах
  • V. Simanenkov
    National Medical Association for the Study of the Multimorbidity
  • I. Maev
    National Medical Association for the Study of the Multimorbidity
  • O. Tkacheva
    National Medical Association for the Study of the Multimorbidity
  • S. Alekseenko
    National Medical Association for the Study of the Multimorbidity
  • D. Andreev
    National Medical Association for the Study of the Multimorbidity
  • D. Bordin
    National Medical Association for the Study of the Multimorbidity
  • T. Vlasov
    National Medical Association for the Study of the Multimorbidity
  • N. Vorobyeva
    National Medical Association for the Study of the Multimorbidity
  • V. Grinevich
    National Medical Association for the Study of the Multimorbidity
  • I. Gubonina
    National Medical Association for the Study of the Multimorbidity
  • M. Drobizhev
    National Medical Association for the Study of the Multimorbidity
  • N. Efremov
    National Medical Association for the Study of the Multimorbidity
  • A. Karateev
    National Medical Association for the Study of the Multimorbidity
  • Y. Kotovskaya
    National Medical Association for the Study of the Multimorbidity
  • I. Kravchuk
    National Medical Association for the Study of the Multimorbidity
  • G. Krivoborodov
    National Medical Association for the Study of the Multimorbidity
  • E. Kulchavenya
    National Medical Association for the Study of the Multimorbidity
  • A. Lila
    National Medical Association for the Study of the Multimorbidity
  • M. Mayevskaya
    National Medical Association for the Study of the Multimorbidity
  • E. Poluektova
    National Medical Association for the Study of the Multimorbidity
  • T. Popkova
    National Medical Association for the Study of the Multimorbidity
  • O. Sablin
    National Medical Association for the Study of the Multimorbidity
  • O. Solovyeva
    National Medical Association for the Study of the Multimorbidity
  • A. Suvorov
    National Medical Association for the Study of the Multimorbidity
  • G. Tarasova
    National Medical Association for the Study of the Multimorbidity
  • D. Trukhan
    National Medical Association for the Study of the Multimorbidity
  • A. Fedotova
    National Medical Association for the Study of the Multimorbidity
Название журнала
  • Cardiovascular Therapy and Prevention (Russian Federation)
Том
  • 20
Выпуск
  • 1
Страницы
  • 121-278
Номер гранта
  • undefined
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus
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