Статья

Organ-preserving procedures as an option for treatment of patients with pancreatic neuroendocrine tumours

A. Kriger, S. Berelavichus, A. Kaldarov, D. Gorin, M. Raevskaya, V. Kazennov, V. Zekster, V. Panteleev,
2021

Objective: Pancreatic neuroendocrine tumour (pNET) is a rare type of tumour with different malignant potential. Nowadays there is no universal approach for treatment of small and benign-looking pNETs throughout the world. Methods: There were 137 patients with pNETs surgically treated in our department between 2007 and 2017. Most of them were female - 96 cases with median age 42 years old. Organ-preserving procedures (OP) were performed in 44 (32%) cases and were compared with standard procedures 93 (68%) cases. Results: Main intraoperative characteristics were comparable in groups. There was significantly less estimated blood loss volume in the OP group: less than 1 dL. Postoperative length of stay and drainage placement time were less in the OP group. There were less pancreatic fistulas and no delayed gastric empties in the OP group. 90-day postoperative mortality rate was the same in both groups: four cases of severe postoperative pancreatitis with acute respiratory distress syndrome. Conclusion: As the “wait-and-see” policy can be not useful due to uncontrolled disease progression, choice of organ-preserving treatment first can become the first line of decision taking in small benign pNETs. Our experience shows that organ-preserving treatment is more comfortable for the surgeon and for the patient. However, it is not the universal position. The long-term survival data still has to be estimated.

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  • 1. Version of Record от 2021-02-01

Метаданные

Об авторах
  • A. Kriger
    Ministry of Health of Russian Federation
  • S. Berelavichus
    Ministry of Health of Russian Federation
  • A. Kaldarov
    Ministry of Health of Russian Federation
  • D. Gorin
    Ministry of Health of Russian Federation
  • M. Raevskaya
    Ministry of Health of Russian Federation
  • V. Kazennov
    Ministry of Health of Russian Federation
  • V. Zekster
    Sechenov First Moscow State Medical University
  • V. Panteleev
    Ministry of Health of Russian Federation
Название журнала
  • Surgical Practice
Том
  • 25
Выпуск
  • 1
Страницы
  • 4-9
Номер гранта
  • undefined
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus