The emergency conditions caused by the coronavirus pandemic in 2020 made the national governments the last resort, which was forced to bear all the financial costs associated with the lockdown in the national economy, with social support of the population and fiscal and monetary help to private firms which business was blocked. Lockdowns, publicly declared in countries around the world to stop the exponential growth of coronavirus-infected patients, have brought unprecedented losses in both human lives and national welfare. As a result, the coronavirus pandemic left two fundamental priorities for the state: (1) to stabilize the epidemiological situation in the country and (2) to reopen the economy in time after the lockdown. On this basis, the term "epinomics"was introduced, which assumes the primary public task to ensure the life and health of citizens, and only under this condition allows the possibility of economic recovery. In this case, the expansion of the practice of implementing public infrastructure projects on the basis of public-private partnership realizes the essence of the state's epinomic strategy. Moreover, in the post-COVID-19 future, infrastructure projects can become an effective form of implementation of the UN "human-first"model, since they allow solving the immediate problems of ordinary citizens mostly affected in 2020. It is about the growth of employment, the provision of workforce wages, development of socially significant infrastructure, which contribution to the economic revival of countries can hardly be overestimated. At the same time, the government through public-private partnership gets the opportunity to directly broadcast to society the results of the effectiveness of its epinomic strategy in stabilizing the epidemiological situation and reopening the economy after the lockdown.