Статья

Standardising definitions for the pre-eclampsia core outcome set: A consensus development study

J. Duffy, A. Cairns, L. Magee, P. von Dadelszen, J. van 't Hooft, C. Gale, M. Brown, L. Chappell, W. Grobman, R. Fitzpatrick, S. Karumanchi, D. Lucas, B. Mol, M. Stark, S. Thangaratinam, M. Wilson, P. Williamson, S. Ziebland, R. McManus, E. Abalos, C. Adamson, A. Akadri, Z. Akturk, K. Allegaert, E. Angel-Müller, J. Antretter, H. Ashdown, F. Audibert, N. Auger, C. Aygun, I. Babic, R. Bagga, J. Baker, Y. Beebeejaun, P. Bhakta, V. Bhandari, S. Bhattacharya, M. Blanker, F. Bloomfield, A. Bof, S. Brennan, K. Broekhuijsen, F. Broughton Pipkin, J. Browne, R. Browning, J. Bull, A. Butt, D. Button, J. Campbell, D. Campbell, L. Carbillon, S. Carthy, E. Casely, J. Cave, J. Cecatti, M. Chamillard, D. Chassard, N. Checheir, V. Chulkov, C. Cluver, C. Crawford, M. Daly, D. Darmochwal-Kolarz, R. Davies, M. Davies, J. Dawson, N. Dobson, C. Dodd, F. Donald, L. Duley, J. Epstein-Mares, O. Erez, E. Evans, R. Farlie, A. Ferris, E. Frankland, D. Freeman, S. Gainder, W. Ganzevoort, O. Gbinigie, M. Gerval, S. Ghosh, L. Gingel, M. Glogowska, A. Goodlife, K. Gough, J. Green, F. Gul, L. Haggerty, D. Hall, M. Hallman, L. Hamilton, S. Hammond, S. Harlow, K. Hays, S. Hickey, M. Higgins, L. Hinton, S. Hobson, M. Hogg,
2020

Objectives: To develop consensus definitions for the core outcome set for pre-eclampsia. Study design: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. Results: Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. Conclusions: Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0.

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  • 1. Version of Record от 2020-07-01

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Об авторах
  • J. Duffy
    University of Oxford Medical Sciences Division, University College London
  • A. Cairns
    University of Oxford Medical Sciences Division
  • L. Magee
    King's College London
  • P. von Dadelszen
    King's College London
  • J. van 't Hooft
    Amsterdam UMC - University of Amsterdam
  • C. Gale
    Imperial College London
  • M. Brown
    UNSW Sydney
  • L. Chappell
    King's College London
  • W. Grobman
    Northwestern University Feinberg School of Medicine
  • R. Fitzpatrick
    University of Oxford Medical Sciences Division
  • S. Karumanchi
    Cedars-Sinai Medical Center
  • D. Lucas
    London North West University Healthcare NHS Trust
  • B. Mol
    Monash University
  • M. Stark
    The University of Adelaide
  • S. Thangaratinam
    Barts and The London School of Medicine and Dentistry
  • M. Wilson
    Faculty of Medicine, Dentistry and Health
  • P. Williamson
    University of Liverpool
  • S. Ziebland
    University of Oxford Medical Sciences Division
  • R. McManus
    University of Oxford Medical Sciences Division
  • E. Abalos
    Centro Rosarino de Estudios Perinatales
  • C. Adamson
    Chelsea and Westminster Hospital NHS Foundation Trust
  • A. Akadri
    Babcock University
  • Z. Akturk
    Ailem Academic Counselling
  • K. Allegaert
    KU Leuven
  • E. Angel-Müller
    Universidad Nacional de Colombia
  • J. Antretter
    Northwell Health
  • H. Ashdown
    University of Oxford
  • F. Audibert
    University of Montreal
  • N. Auger
    Centre Hospitalier de L'Universite de Montreal
  • C. Aygun
    Ondokuz Mayis Üniversitesi
  • I. Babic
    Prince Sultan Military Medical City
  • R. Bagga
    Postgraduate Institute of Medical Education & Research, Chandigarh
  • J. Baker
  • Y. Beebeejaun
    King's Fertility
  • P. Bhakta
    University Hospital Limerick
  • V. Bhandari
    Drexel University
  • S. Bhattacharya
    University of Aberdeen
  • M. Blanker
    University of Groningen
  • F. Bloomfield
    The University of Auckland
  • A. Bof
  • S. Brennan
  • K. Broekhuijsen
    Haaglanden Medisch Centrum
  • F. Broughton Pipkin
    University of Nottingham Medical School
  • J. Browne
    Utrecht University
  • R. Browning
    King Edward Memorial Hospital for Women
  • J. Bull
  • A. Butt
  • D. Button
  • J. Campbell
    Imperial College Healthcare NHS Trust
  • D. Campbell
    University of Aberdeen
  • L. Carbillon
    Hopital Jean-Verdier
  • S. Carthy
  • E. Casely
  • J. Cave
    Downland Practice
  • J. Cecatti
    Universidade Estadual de Campinas
  • M. Chamillard
    Centro Rosarino de Estudios Perinatales
  • D. Chassard
    Université de Lyon
  • N. Checheir
    University of North Carolina School of Medicine
  • V. Chulkov
    South Ural State Medical University
  • C. Cluver
    Stellenbosch University
  • C. Crawford
    University of Oxford
  • M. Daly
    Irish Neonatal Health Alliance
  • D. Darmochwal-Kolarz
    University of Rzeszów
  • R. Davies
  • M. Davies
    Royal Brisbane and Women's Hospital
  • J. Dawson
    Nottingham University Hospitals NHS Trust
  • N. Dobson
  • C. Dodd
    University Hospitals of Leicester NHS Trust
  • F. Donald
    North Bristol NHS Trust
  • L. Duley
    University of Nottingham
  • J. Epstein-Mares
  • O. Erez
    Ben-Gurion University of the Negev
  • E. Evans
    St George's University Hospitals NHS Foundation Trust
  • R. Farlie
    Hospitalsenhed Midt
  • A. Ferris
  • E. Frankland
  • D. Freeman
    University of Glasgow
  • S. Gainder
    Post Graduate Institute of Medical Education and Research
  • W. Ganzevoort
    Amsterdam Universitair Medische Centra
  • O. Gbinigie
  • M. Gerval
    Chelsea and Westminster Hospital NHS Foundation Trust
  • S. Ghosh
    All India Institute of Medical Sciences, Patna
  • L. Gingel
  • M. Glogowska
    University of Oxford
  • A. Goodlife
    University Hospitals of Leicester NHS Trust
  • K. Gough
    Luton and Dunstable University Hospital
  • J. Green
  • F. Gul
    Khyber Medical University
  • L. Haggerty
    Midwife Mid Essex Hospitals NHS Trust
  • D. Hall
    Stellenbosch University
  • M. Hallman
    Oulun Yliopisto
  • L. Hamilton
  • S. Hammond
    St George's University Hospitals NHS Foundation Trust
  • S. Harlow
    University of Michigan
  • K. Hays
    Bastyr University
  • S. Hickey
  • M. Higgins
    Irish Nurses and Midwives Organisation
  • L. Hinton
    University of Oxford
  • S. Hobson
    University of Toronto
  • M. Hogg
    Barts Health NHS Trust
Название журнала
  • Pregnancy Hypertension
Том
  • 21
Страницы
  • 208-217
Финансирующая организация
  • Chiesi Farmaceutici
Номер гранта
  • GNT1082548
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus