This article examines agriculture in the Russian Far East through the prism of recent crises. A comparative analysis of the indicators of food self-sufficiency in the Russian Federation and its macro-regions is carried out; forecast estimates of the level of their food self-sufficiency are predicted. In order to identify a group of commodity producers capable of overcoming the challenges that the agriculture in the Far East has faced, a factor model of the growth rate of agricultural production in the Far East is built, its adequacy is proven, and elasticity coefficients are calculated. The category of land users that should become a vector for overcoming the crisis in the region's agricultural sector is determined.