COVID-19.рф: ИНФОРМАЦИЯ ПРОТИВ ПАНДЕМИИ

Поиск по репозиторию

Статья

Rapid spread of influenza A(H1N1)pdm09 viruses with a new set of specific mutations in the internal genes in the beginning of 2015/2016 epidemic season in Moscow and Saint Petersburg (Russian Federation)

A. Komissarov, A. Fadeev, M. Sergeeva, S. Petrov, K. Sintsova, A. Egorova, M. Pisareva, Z. Buzitskaya, T. Musaeva, D. Danilenko, N. Konovalova, P. Petrova, K. Stolyarov, E. Smorodintseva, E. Burtseva, K. Krasnoslobodtsev, E. Kirillova, L. Karpova, M. Eropkin, A. Sominina, M. Grudinin,
2021
https://doi.org/10.1111/irv.12389

A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection (ARI) and in number of lethal cases. We performed antigenic analysis of 108 and whole-genome sequencing of 77 influenza A(H1N1)pdm09 viruses from Moscow and Saint Petersburg. Most of the viruses were antigenically related to the vaccine strain. Whole-genome analysis revealed a composition of specific mutations in the internal genes (D2E and M83I in NEP, E125D in NS1, M105T in NP, Q208K in M1, and N204S in PA-X) that probably emerged before the beginning of 2015/2016 epidemic season. © 2016 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Цитирование

Похожие публикации

Influenza epidemiology and influenza vaccine effectiveness during the 2015-2016 season: Results from the Global Influenza Hospital Surveillance Network
J. Puig-Barberà, A. Mira-Iglesias, E. Burtseva,
Malignant neoplasms mortality rates in Moscow and Saint Petersburg in 2015 and 2018 [Смертность населения от злокачественных новообразований в Москве и Санкт-Петербурге в 2015 и 2018 годах]
I. Samorodskaya, V. Semenov,
The 2015-2016 epidemic season in Russia and the world: Circulation of influenza viruses, trendsin incidence, clinical aspects, and treatment algorithm
D. Lvov, L. Kolobukhina, E. Burtseva,

Источник

Версии

  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • A. Komissarov
    Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, Laboratory of Molecular Virology and Genetic Engineering, WHO-recognized National Influenza Centre of Russian Federation, Saint Petersburg, Russian Federation
  • A. Fadeev
    Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, Laboratory of Influenza Vaccines, Saint Petersburg, Russian Federation
  • M. Sergeeva
    Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, Laboratory of Molecular Virology and Genetic Engineering, Saint Petersburg, Russian Federation
  • S. Petrov
    Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, Laboratory of Evolutionary Variability of Influenza Viruses, WHO-recognized National Influenza Centre of Russian Federation, Saint Petersburg, Russian Federation
  • K. Sintsova
    Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, Department of IT, WHO-recognized National Influenza Centre of Russian Federation, Saint Petersburg, Russian Federation
  • A. Egorova
    Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, Laboratory of Biotechnology, WHO-recognized National Influenza Centre of Russian Federation, Saint Petersburg, Russian Federation
  • M. Pisareva
    Federal Research Center of Epidemiology and Microbiology named after N. F. Gamaleya, WHO-recognized National Influenza Centre of Russian Federation, Moscow, Russian Federation
  • Z. Buzitskaya
    Research Institute of Influenza, Laboratory of Influenza and ARI Epidemiology, WHO-recognized National Influenza Centre of Russian Federation, Saint Petersburg, Russian Federation
  • T. Musaeva
  • D. Danilenko
  • N. Konovalova
  • P. Petrova
  • K. Stolyarov
  • E. Smorodintseva
  • E. Burtseva
  • K. Krasnoslobodtsev
  • E. Kirillova
  • L. Karpova
  • M. Eropkin
  • A. Sominina
  • M. Grudinin
Название журнала
  • Influenza and other Respiratory Viruses
Том
  • 10
Выпуск
  • 4
Страницы
  • 247-253
Ключевые слова
  • influenza vaccine; M1 protein; nonstructural protein 1; unclassified drug; virus protein; amino acid substitution; antigenic analysis; Article; controlled study; gene sequence; genetic analysis; Influenza A virus (H1N1); nonhuman; priority journal; Russian Federation; seasonal influenza; virus gene; virus genome; virus mutation; virus strain; virus transmission
Издатель
  • Blackwell Publishing Ltd
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus
COVID-19.рф: Информация против пандемии

Адрес: 115114, Москва, ул. Летниковская, д. 4, стр.5, офис 2.4
тел.\факс: +7(499)754-99-94, доб. 502
e-mail: covid19@neicon.ru

Проект реализуется с использованием гранта Президента Российской Федерации на развитие гражданского общества, предоставленного Фондом президентских грантов.

Содержимое сайта, если не указано иное, опубликовано в соответствии с лицензией Creative Commons «Attribution» («Атрибуция») 4.0 Всемирная (CC BY 4.0). Права на материалы, переданные партнерами проекта, принадлежат их правообладателям.

© 2025 NEICON