Статья

Lessons learned from and prospects of using mobile laboratories for epidemiological surveillance over plague, other particularly dangerous, natural-focal, zoonotic infectious diseases [опЫт и перСпективЫ иСпольЗования моБильнЫх лаБораторий при проведении эпидемиологичеСкого надЗора За чумой, другими оСоБо опаСнЫми, природно-очаговЫми, ЗооноЗнЫми инфекционнЫми БолеЗнями]

I. Sharova, T. Krasovskaya, E. Kazorina, A. Kazantsev, M. Proskuryakova, V. Kuklev, S. Shcherbakova, V. Kutyrev, R. Adilov, E. Bulycheva, A. Troitskaya, B. Agapov, I. Akimov, O. Balgan, N. Chumakova, V. Tkachenko, E. Glushkov, E. Rozhdestvensky, G. Bazarova, A. Mishchenko, G. Mukhturgin,
2021

The review presents the materials on the use of mobile laboratories, developed in the Russian Federation, in the framework of four main areas: monitoring of territories to identify the circulation of pathogens of natural-focal infectious diseases; monitoring of territories during the exacerbation of the epizootic situation; participation in the elimination of outbreaks of infectious diseases; monitoring of territories to control and predict the epidemiological and epizootiologic situation in preparation for mass events. The tactical and technical characteristics and the procedure for organizing the operation of the mobile laboratory for monitoring and diagnostics mounted on the platform of the KamAZ chassis are considered. A distinctive feature of the laboratory from the existing Russian and foreign counterparts is the availability of the necessary conditions for conducting research using bacteriological analysis, rapid and accelerated diagnostic methods, and performing a full cycle of works – from the preparatory stage to the destruction of infected material. High-tech equipment allows the realization of two research schemes: the first – bacteriological analysis alongside the PCR, which ensures high reliability of the results; the second – conducting the PCR at the first stage, and when identifying genetic markers of the pathogen – performing bacteriological analysis of positive samples in order to isolate the culture of the pathogen and identify it subsequently. The second scheme will reduce the volume of bacteriological studies; make changes in the tactics of epizootiological survey. Tests of the mobile laboratory have demonstrated the effectiveness of its use in the epizootiological examination of natural plague foci, including cross-border ones. Owing to the use of a mobile laboratory in the Gorno-Altaisk high-mountain natural focus of plague, a new epizootic site was identified, located in a remote area, used by the population as a summer pasture for grazing domestic animals. The use of mobile laboratories will strengthen the laboratory base of institutions that monitor particularly dangerous, natural-focal and other dangerous infectious diseases; will help to bring the advanced diagnostic technologies directly to the natural focus, reduce the risk of epidemic complications due to plague and other particularly dangerous infections in cross-border natural foci. © 2020 Russian Research Anti-Plague Institute. All rights reserved.

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Версии

  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • I. Sharova
    Russian Research Anti-Plague Institute “Microbe”., 46, Universitetskaya St., Saratov, 410005, Russian Federation
  • T. Krasovskaya
    Astrakhan Plague Control Station., 3, Kubanskaya St., Astrakhan, 414000, Russian Federation
  • E. Kazorina
    Tuva Plague Control Station., 13, Moskovskaya St., Kyzyl, 667010, Russian Federation
  • A. Kazantsev
    Altai Plague Control Station., 2, Zavodskaya St., Gorno-Altaisk, 649002, Russian Federation
  • M. Proskuryakova
    Irkutsk Research Anti-Plague Institute of Siberia and Far East. 78, Trilissera St., Irkutsk, 664047, Russian Federation
  • V. Kuklev
  • S. Shcherbakova
  • V. Kutyrev
  • R. Adilov
  • E. Bulycheva
  • A. Troitskaya
  • B. Agapov
  • I. Akimov
  • O. Balgan
  • N. Chumakova
  • V. Tkachenko
  • E. Glushkov
  • E. Rozhdestvensky
  • G. Bazarova
  • A. Mishchenko
  • G. Mukhturgin
Название журнала
  • Problemy Osobo Opasnykh Infektsii
Выпуск
  • 4
Страницы
  • 26-33
Издатель
  • Russian Research Anti-Plague Institute
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus