api.elsevier.com/content/article/pii/S1359610120301088doi:10.1016/j.cytogfr.2020.05.0091-s2.0-S135961012030108810.1016/j.cytogfr.2020.05.009S1359-6101(20)30108-8IL... ///IL-6: Relevance for immunopathology of SARS-CoV-2... This review discusses the mechanisms by which IL-6 may possibly contribute to disease exacerbation and the potential of therapeutic approaches based on anti-IL-6 biologics. © 2020 The Authors...

IL-6Р состо- ит из двух цепей: IL-6-связывающей цепи (IL-6Рα) и трансмембранного белка gp130 (130 kDa glycopro­ tein; IL-6Рβ), который является сигнальным рецеп- тором.... ///Coronavirus disease-2019 (COVID-19): Value of IL-6 inhibitors... In the spectrum of cytokines involved in the pathogenesis of cytokine storm syndrome in IMIRDs and COVID-19, great importance is attached to the pro-inflammatory cytokine, interleukin IL-6....

///IL-21/CD40L stimulation of human B-lymphocytes in vitro and their characteristics... When feeder cells and B lymphocytes were co-cultured in the presence of exogenous IL-21, stimulation of B lymphocytes was observed. B lymphocytes began to proliferate and after 7 days their number increased by an average of 8 times....

Так из 6 цитокинов воспаления (TNFα, IL-1β, IL-6, IL-8, IL-17 и IFNγ) в перифериче- ской крови больных тяжелой формой гриппа А(H1N1)pdm09 наиболее резким (в 20 раз выше нормы) было повышение уровня IL-6 [5].... ///Meta-analysis of the research of IL-6 in peripheral blood of patients with influenza a(H1N1)PDM09... to accumulate research experience level IL-6 on one and the same test systems and laboratory equipment....

Патогенетическая значимость применения гуманизированного моноклонального антитела к рецептору ИЛ6-α (тоцилизумаб) в терапии иммуновоспалительных заболеваний///Pathogenetic significance of the use of a humanized monoclonal antibody to the IL-6-α receptor... Currently, the use of a humanized monoclonal antibody to the IL-6α receptor (tocilizumab) is one of the most promising directions in the treatment of rheumatoid arthritis, systemic lupus erythematosus, systemic scleroderma, large arterial vasculitis –...

Методом мультиплексного анализа по технологии xMAP опреде- ляли концентрации 46 молекул: IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A/CTLA8, IL-17-E/IL-25, IL-17F, IL-18, IL-22, IL-27, IFNα2,... Concentrations of 46 molecules, such as IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A/CTLA8, IL-17-E/IL-25, IL-17F, IL-18, IL-22, IL-27, IFNα2, IFNγ, TNFα, TNFβ/ Lymphotoxin-α (LTA), CCL2/MCP-1,...

Pro- inflammatory activity of cytokines was assessed by the level of interleu- kins (IL): IL-1β, IL-6, IL-10. Results.... Proinflammatory activity of cytokines was assessed by the level of interleukins (IL): IL-1β, IL-6, IL-10. Results....

rates and increased IL-6 production in the lungs....

-6 до сорбции Дельта IL-6 IL-18 до сорбции Дельта IL-18 Рис. 1.... The potential association between received data (IL-6, IL-18, delta of IL-6, delta of IL-18) and degree of lung damage and outcomes was analyzed. Results....

The mRNA expression and cytokine secretion levels of IL-1β, IL-6, TNF-α and IL‐18 were assessed by Real‐time PCR and ELISA, respectively....