Patients with the new coronavirus infection (COVID-19) may need rehabilitation. Approaches to rehabilitation of patients with other conditions also have to be revised under the conditions of the SARS-CoV-2 epidemic. There is a need in clinical recommendations for delivery of rehabilitation care to patients with COVID-19 and other diseases during the pandemic. A group of experts analyzed real life reports on rehabilitation in COVID-19, along with earlier studies on rehabilitation in Post-intensive care syndrome (PICS) and acute respiratory distress syndrome of non-coronavirus etiology, and used them to develop the main points for clinical recommendations. We discuss the major rehabilitation problems in COVID-19 patients determining their needs in care, in particular, the structural and functional impairments leading to limitations of self-care, mobility, everyday life, communication, interpersonal relations, and professional activities. We provide general recommendations on managing medical rehabilitation in the pandemic at all three phases, including patients routing and safeguarding medical personnel and patients against the infection. We identify essential components of individual rehabilitation program for COVID-19 patients at all phases of rehabilitation, including patient examination, correction of nutritional deficiencies, improvement of respiratory function, exercise tolerance, and muscle strength, self-monitoring and training in new movement conditions; recovery of psychoemotional state and cognitive functions, as well as independence in everyday life. Medical rehabilitation during the COVID-19 epidemic should include all components of rehabilitation care and help in optimizing vital functions, preventing complications and improving the patient’s life quality.