The article aims to determine the components of the teachers’ readiness to organize student interaction in an electronic information and educational environment considering the difficulties that occur while planning the instruction and student interaction. The main research methods were the analysis of scientific and methodological literature, surveys, and correlation analysis. The practical significance of the study includes the development of recommendations for improving the teachers’ readiness to organize student interaction in an electronic information and educational environment, which is especially important not only during the pandemic, but also in everyday educational practice. The research findings determine the direction for further research on the modernization of the education system as a whole, and they may be used by the teachers of higher educational institutions when organizing learning under the conditions of intense digitalization of education and by the heads of educational institutions.