At the Yaroslav-the-Wise Novgorod State University (Russia, Veliky Novgorod, ul. Bolshaya Sankt-Peterburgskaya, 41) on November 5-6, 2020, the International Scientific and Practical Conference “Mathematical Modeling, Programming and Applied Mathematics” will be held for the second time. Major scientists from Moscow and St. Petersburg, Kazan and Voronezh and Tver, and other cities of Russian Federation and from Belarus, Bulgaria, Kazakhstan, Ukraine, China, USA, Egypt, submitted their applications and articles. Despite the difficult situation associated with the spread of COVID-19, the interest in the conference is quite considerable. The scientists – participants of the conference – present their latest scientific achievements, exchange experience and discuss issues of mathematical modeling in applied mathematics, programming, physics. Also, the conference participants will analyze and evaluate innovative solutions in terms of their relevance, effectiveness and prospects for further development. The conference will include plenary sessions and 8 scientific sections. An auditorium equipped with the necessary computer equipment for online broadcasting is provided for each section. List of International Program Committee, Organizing Committee, Editorial Committee, Invited Speakers and Organizing Institution are available in this pdf.