Introduction. The article presents information on the activities of inpatient facilities for infectious diseases during the pandemic of the new coronavirus disease 2019, taking into account current regulatory documents. The authors reviewed the principles of hospital zoning and patient controlled movement in hospitals for infectious diseases. The paper deals with the organization of the admission departments and equipment of the diagnostic units of hospitals for infectious diseases, providing a graphical presentation of an individual isolation unit (Melzer box) including description of the control and management system for safe access to infectious units. The characteristics of engineering and communication systems, disposal of hazardous medical waste, catering, navigation systems, operational remote communication between doctors and patients, application of barcoding for patient identification and medical records are also discussed. The purpose of this paper was to: Identify the shortcomings of the existing regulatory framework concerning the management and organization of health care institutions that provide medical care to patients with the new coronavirus infection; Identify areas that require adjustments, given the modern requirements for high quality treatment, as well as to ensure epidemiological safety for medical staff and patients; Specify additional requirements for hospitals for infectious diseases, which should be taken into account when planning major repairs, reconstruction and construction of new medical facilities for providing health care during the pandemic of new coronavirus disease 2019 and other highly infectious infections.