Статья

Molecular profile of oral fluid in new coronavirus infection.

F. Gilmiyarova, O. Gusyakova, D. Konstantinov, I. Selezneva, I. Borodina, N. Kolotyeva, E. Konstantinova, V. Tlustenko, S. Lebedeva, E. Temnik, V. Remizov,
2021

Oral fluid is an alternative biological material that confirms correlations with blood parameters in various pathological conditions of the body. In order to find a non-invasive approach to stratification of patients with COVID-19 disease, molecular biomarkers of the oral fluid have been determined in patients with moderate coronavirus infection in comparison with clinically healthy individuals. It has been shown that proteomic, carbohydrate, macro- and microelement profiles of the oral fluid in coronavirus infection can be used for diagnostics. The features of protein metabolism were revealed: an increase in the content of total protein, urea; increased activity of enzymes aspartate aminotransferase, gamma glutamyl transpeptidase, creatine phosphokinase, alkaline phosphatase; changes in carbohydrate metabolism, which is expressed by an increase in glucose and lactate levels, an increase in lactate dehydrogenase activity, sodium, chloride, calcium, magnesium, iron content.

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Версии

  • 1. Version of Record от 2021-03-30

Метаданные

Об авторах
  • F. Gilmiyarova
    Samara State Medical University.
  • O. Gusyakova
    Samara State Medical University.
  • D. Konstantinov
    Samara State Medical University.
  • I. Selezneva
    Samara State Medical University.
  • I. Borodina
    Samara State Medical University.
  • N. Kolotyeva
    Samara State Medical University.
  • E. Konstantinova
    Samara State Medical University.
  • V. Tlustenko
    Samara State Medical University.
  • S. Lebedeva
    Samara State Medical University.
  • E. Temnik
    Samara State Medical University.
  • V. Remizov
    Samara State Medical University.
Название журнала
  • Laboratornoe Delo
Том
  • 66
Выпуск
  • 3
Страницы
  • 133-138
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • dimensions