The purpose of the article is to identify the main measures of populists to combat the removal of COVID 19 on the example of the United States of America and Italy. The study analyzes populist leaders across the political spectrum coped with the COVID-19 outbreak. The observation shows how, in the example of the United States, Italy such as their optimistic bias and complacency, ambiguity and ignorance of science. The study analyzes the measures taken by the Italian government and the US President. The results of the research allow us to use its materials and theoretical results primarily in political science. They can also be used in the development of specialized courses on modern globalization processes, political leadership, party development, and multiculturalism policy.