Статья

Manifesto on united airways diseases (UAD): an Interasma (global asthma association – GAA) document

A. Tiotiu, P. Novakova, I. Baiardini, A. Bikov, H. Chong-Neto, J. de-Sousa, A. Emelyanov, E. Heffler, G. Fogelbach, K. Kowal, M. Labor, S. Mihaicuta, D. Nedeva, S. Novakova, P. Steiropoulos, I. Ansotegui, J. Bernstein, L. Boulet, G. Canonica, L. Dubuske, C. Nunes, J. Ivancevich, P. Santus, N. Rosario, T. Perazzo, F. Braido,
2021

OBJECTIVE: The large amount of evidence and the renewed interest in upper and lower airways involvement in infectious and inflammatory diseases has led Interasma (Global Asthma Association) to take a position on United Airways Diseases (UAD). METHODS: Starting from an extensive literature review, Interasma executive committee discussed and approved this Manifesto developed by Interasma scientific network (INES) members. RESULTS: The manifesto describes the evidence gathered to date and defines, states, advocates, and proposes issues on UAD (rhinitis, rhinosinusitis and nasal polyposis), and concomitant/comorbid lower airways disorders (asthma, chronic obstructive pulmonary disease, bronchiectasis, cystic fibrosis, obstructive sleep apnoea) with the aim of challenging assumptions, fostering commitment, and bringing about change. UAD refers to clinical pictures characterized by the coexistence of upper and lower airways involvement, driven by a common pathophysiological mechanism, leading to a greater burden on patient's health status and requiring an integrated diagnostic and therapeutic plan. The high prevalence of UAD must be taken into account. Upper and lower airways diseases influence disease control and patient's quality of life. CONCLUSIONS: Patients with UAD need to have a timely and adequate diagnosis, treatment, and, when recommended, referral for management in a specialized center. Diagnostic testing including skin prick or serum specific IgE, lung function, fractional exhaled nitric oxide (FeNO), polysomnography, allergen-specific immunotherapies, biological therapies and home based continuous positive airway pressure (CPAP) whenever these are recommended, should be part of the management plan for UAD. Education of medical students, physicians, health professionals, patients and caregivers on the UAD is needed.

Цитирование

Похожие публикации

Версии

  • 1. Version of Record от 2021-03-05

Метаданные

Об авторах
  • A. Tiotiu
    Department of Pulmonology, University Hospital of Nancy, Nancy, France., EA 3450 DevAH - Development, Adaptation and Disadvantage, Cardiorespiratory Regulations and Motor Control, University of Lorraine, Nancy, France.
  • P. Novakova
    Clinic of Clinical Allergy, Medical University Sofia, Sofia, Bulgaria.
  • I. Baiardini
    Department of Biomedical Sciences, Humanitas University, Milan, Italy.
  • A. Bikov
    Manchester University NHS Foundation Trust, Manchester, United Kingdom., Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.
  • H. Chong-Neto
    Division of Allergy and Immunology, Department of Pediatrics, Federal University of Paraná, Curitiba, Brazil.
  • J. de-Sousa
    Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal., ICVS/3B's, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
  • A. Emelyanov
    Department of Respiratory Medicine, North-Western Medical University named after I.I.Mechnikov, St-Petersburg, Russia.
  • E. Heffler
    Department of Biomedical Sciences, Humanitas University, Milan, Italy., Personalized Medicine, Asthma & Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, MI, Italy.
  • G. Fogelbach
    Clinic of Clinical Allergy, Medical University Sofia, Sofia, Bulgaria., Instituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Laboratorio de Bioquímica Estructural, Ciudad de México, México.
  • K. Kowal
    Department of Allergology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland.
  • M. Labor
    Värnamo Hospital, Jönköping district, Sweden.
  • S. Mihaicuta
    Pulmonology Department, Cardio Prevent Foundation, University of Medicine and Pharmacy "Dr Victor Babes", Timisoara, Romania.
  • D. Nedeva
    Clinic of Clinical Allergy, Medical University Sofia, Sofia, Bulgaria.
  • S. Novakova
    Allergy Unit of Internal Consulting Department, University Hospital "St. George", Plovdiv, Bulgaria.
  • P. Steiropoulos
    Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
  • I. Ansotegui
    Hospital Quirónsalud Bizkaia, Bilbao, Spain.
  • J. Bernstein
    Department of Internal Medicine, Division of Immunology, Allergy Section University of Cincinnati, Cincinnati, OH, USA.
  • L. Boulet
    Québec Heart and Lung Institute-Laval University, Québec City, Canada.
  • G. Canonica
    Department of Biomedical Sciences, Humanitas University, Milan, Italy., Personalized Medicine, Asthma & Allergy, Humanitas Clinical and Research Center, IRCCS, Rozzano, MI, Italy.
  • L. Dubuske
    Division of Allergy and Immunology, Department of Internal Medicine, George Washington University School of Medicine and Health Sciences, George Washington University Medical Faculty Associates, Washington, DC, USA.
  • C. Nunes
    Centro de ImmunoAlergologia de Algarve, Porto, Portugal.
  • J. Ivancevich
    Immunology Department, Faculty of Medicine, del Salvador University, Buenos Aires, Argentina.
  • P. Santus
    Department of Biomedical and Clinical Sciences, University of Milan, Division of Respiratory Diseases "L. Sacco" Hospital, ASST Fatebenefratelli Sacco, Milan, Italy.
  • N. Rosario
    Federal University of Paraná (UFPR), Curitiba, Brazil.
  • T. Perazzo
    Department of Internal Medicine, University of Genoa, Genova, Italy.
  • F. Braido
    Department of Internal Medicine, University of Genoa, Genova, Italy., Respiratory Unit for Continuity of Care IRCCS, Ospedale Policlinico San Martino, Genova, Italy.
Название журнала
  • Journal of Asthma
Страницы
  • 1-16
Издатель
  • Taylor & Francis
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • dimensions