A brief review is dedicated to the latest advances in the field of non-invasive studies of capillary blood flow in humans based on the developments of Russian scientists. Modern computer technologies have significantly expanded the capabilities of researchers and make it possible to obtain information about fundamental processes at the level of the metabolic link of the vascular bed not only in a hospital setting, but also in a remote access mode, which is extremely important in the context of a pandemic caused by the SARS-CoV-2 virus.