Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19

V. Khavinson; B. Kuznik; V. Volchkov; S. Rukavishnikova; O. Titova; T. Akhmedov; S. Trofimova; G. Ryzhak; V. Potyomkin; U. Saginbaev

Статья

Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19

V. Khavinson, B. Kuznik, V. Volchkov, S. Rukavishnikova, O. Titova, T. Akhmedov, S. Trofimova, G. Ryzhak, V. Potyomkin, U. Saginbaev,

2021

https://doi.org/10.30629/0023-2149-2020-98-8-593-599

Results of comparative assessment of level of antibodies of IgG to SARS-CoV-2 in dynamics at standard and complex methods of treatment with use of medicinal peptide medicine of a timus of a timalin for patients with COVID-19 are presented in article. It was found that as a result of standard treatment, patients showed a decrease in antibody levels by 53% after 104 days. The addition of thymalin to standard therapy slowed down the decline of this indicator. So, a similar indicator in patients who took thymalin was only 21%. This contributed to maintaining strained adaptive immunity. The detected immunomodulatory properties of the preparation of thymalin with respect to COVID-19 can be reflected both in the formation of an effective immune layer of the population through natural immunization, and in the process of antibody formation during vaccination of target contingents.

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1. Version of Record от 2021-02-07

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Об авторах

V. Khavinson
Saint Petersburg Institute of Bioregulation and Gerontology; I.P. Pavlov Institute of Physiology of the Russian Academy of Sciences
B. Kuznik
Chita State Medical Academy
V. Volchkov
Saint Petersburg City Multiprofile Hhospital №2
S. Rukavishnikova
Saint Petersburg City Multiprofile Hhospital №2; Saint Petersburg State I.P. Pavlov Medical University
O. Titova
Saint Petersburg State I.P. Pavlov Medical University
T. Akhmedov
Saint Petersburg City Multiprofile Hhospital №2; Saint Petersburg State I.P. Pavlov Medical University
S. Trofimova
Saint Petersburg Institute of Bioregulation and Gerontology
G. Ryzhak
Saint Petersburg Institute of Bioregulation and Gerontology
V. Potyomkin
Saint Petersburg City Multiprofile Hhospital №2; Saint Petersburg State I.P. Pavlov Medical University
U. Saginbaev
Saint Petersburg State I.P. Pavlov Medical University

Название журнала

Clinical Medicine (Russian Journal)

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Выпуск

Страницы

593-599

Издатель

Medical Informational Agency Publishers

Тип документа

journal article

Тип лицензии Creative Commons

CC BY

Правовой статус документа

Свободная лицензия

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Статья

Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19

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