The article shows that the epidemiological situation has significantly slowed down economic growth not only in Russia, but also in all countries of the world, which causes new challenges and threats in achieving the sustainable development Goals. This increases the importance of government support aimed at the recovery of employment and income, growth and long-term structural changes in the economy, with software-targeted and implemented under the state programs and projects at both the Federal and regional levels. In our country, unprecedented and decisive actions are being taken within the framework of state support to restore effective employment and effective demand, improve the business climate and economic growth in the context of the sustainable development goals. At the same time, in the context of global integration, when the economies of all countries of the world are becoming increasingly dependent on each other, strengthening international cooperation and developing multilateral partnerships between countries should be considered as one of the important factors for mitigating the consequences of the COVID-19 pandemic and sustainable development of the national economy in the long term.