The aim of the paper is to analyze the measures taken by the government of India to prevent the spread of coronavirus infection among the population, as well as to mitigate the impact of COVID-19 pandemic on the activities of companies and enterprises and to prevent a socio-economic crisis. The main shortcomings and positive results achieved by the government of India, state and city administrations in the fight against COVID-19 are identified using bibliographic and comparative analysis methods and taking into account the historical context. The authors conclude that the existing “Epidemic Diseases Act,” 1897, which is applied as the main normative act regulating the epidemiological situation in the country, does not take into account all the factors and conditions of the spread of infectious diseases in the modern world and does not reflect the reality in terms of effective response to the outbreak of coronavirus disease.