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Статья
Treatment of covid-19 from the perspective of endotheliopathy correction and prevention of thrombotic complications. The agreed position of the experts
2021
The proposed consensus position of the experts present approaches to the diagnosis, treatment and secondary prevention of throm-botic complications and endothelial dysfunction in COVID-19 for their use in outpatient visits. Experts confirmed the position of LMWH in hospitalized patients. Parnaparin sodium is the optimal choice for these patients, due to strong anti-inflammatory effect and a convenient dosing regimen. Experts confirmed endothelial damage as an important factor in the development of hyper-coagulation in outpatients with COVID-19. According to expert’s consensus position, sulodexide may be a pathogenetic approach for the problem of endothelial dysfunction, especially — for period of convalescence. Experts recommend to introduce of sulo-dexide into the Temporary methodological recommendations of the Ministry of Health of the Russian Federation: for outpatients with light forms COVID-19, for patients with high risk of bleeding, also — for patients at the stage of rehabilitation to prevent recurrent VTE and reduce the risk of developing pulmonary fibrosis.
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