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Статья
Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multinational cohort
N. Papadopoulos,
A. Mathioudakis,
A. Custovic,
A. Deschildre,
W. Phipatanakul,
G. Wong,
P. Xepapadaki,
R. Abou-Taam,
I. Agache,
J. Castro-Rodriguez,
Z. Chen,
P. Cros,
J. Dubus,
Z. El-Sayed,
R. El-Owaidy,
W. Feleszko,
V. Fierro,
A. Fiocchi,
L. Garcia-Marcos,
A. Goh,
E. Hossny,
Y. Huerta Villalobos,
T. Jartti,
P. Le Roux,
J. Levina,
A. López García,
Á. Ramos,
M. Morais-Almeida,
C. Murray,
K. Nagaraju,
M. Nagaraju,
E. Navarrete Rodriguez,
L. Namazova-Baranova,
A. Nieto Garcia,
C. Pozo Beltrán,
T. Ratchataswan,
D. Rivero Yeverino,
E. Rodríguez Zagal,
C. Schweitzer,
M. Tulkki,
K. Wasilczuk,
D. Xu,
A. Alekseeva,
B. Almeida,
M. Andre,
P. Arimova,
A. Blonde,
A. Cunningham,
S. Da Mota,
K. Efendieva,
V. Kalugina,
S. Kiefer,
A. Klein,
C. López,
J. López,
C. Moratellti,
M. Fuentes Pérez,
M. Simermann,
J. Tapia,
A. Tatopoulos,
E. Vishneva,
Κ. Volkov,
L. Bacharier,
M. Bonini,
T. Craig,
Z. Diamant,
F. Ducharme,
J. Gern,
J. Grigg,
E. Hamelmann,
G. Hedlin,
T. Jartti,
O. Kalayci,
A. Kaplan,
J. Konradsen,
P. Kuna,
S. Lau,
P. Le Souef,
R. Lemanske,
M. Makela,
P. Matricardi,
R. Gómez,
M. Miligkos,
P. Pitrez,
D. Price,
P. Pohunek,
G. Roberts,
A. Sheikh,
I. Tsiligianni,
S. Turner,
A. Valiulis,
T. Winders,
O. Yusuf,
H. Zar,
2021
Background: The interplay between COVID-19 pandemic and asthma in children is still unclear. We evaluated the impact of COVID-19 pandemic on childhood asthma outcomes. Methods: The PeARL multinational cohort included 1,054 children with asthma and 505 non-asthmatic children aged between 4 and 18 years from 25 pediatric departments, from 15 countries globally. We compared the frequency of acute respiratory and febrile presentations during the first wave of the COVID-19 pandemic between groups and with data available from the previous year. In children with asthma, we also compared current and historical disease control. Results: During the pandemic, children with asthma experienced fewer upper respiratory tract infections, episodes of pyrexia, emergency visits, hospital admissions, asthma attacks, and hospitalizations due to asthma, in comparison with the preceding year. Sixty-six percent of asthmatic children had improved asthma control while in 33% the improvement exceeded the minimal clinically important difference. Pre-bronchodilatation FEV and peak expiratory flow rate were improved during the pandemic. When compared to non-asthmatic controls, children with asthma were not at increased risk of LRTIs, episodes of pyrexia, emergency visits, or hospitalizations during the pandemic. However, an increased risk of URTIs emerged. Conclusion: Childhood asthma outcomes, including control, were improved during the first wave of the COVID-19 pandemic, probably because of reduced exposure to asthma triggers and increased treatment adherence. The decreased frequency of acute episodes does not support the notion that childhood asthma may be a risk factor for COVID-19. Furthermore, the potential for improving childhood asthma outcomes through environmental control becomes apparent. 1
Цитирование
Похожие публикации
N. Papadopoulos,
A. Mathioudakis,
A. Custovic,
H. Brough,
O. Kalayci,
A. Sediva,
Версии
- 1. Version of Record от 2021-01-01
Метаданные
Об авторах
-
N. Papadopoulos
Faculty of Biology, Medicine and Health, National and Kapodistrian University of Athens -
A. Mathioudakis
Faculty of Biology, Medicine and Health, Wythenshawe Hospital -
A. Custovic
Imperial College London -
A. Deschildre
Université de Lille -
W. Phipatanakul
Children's Hospital Boston -
G. Wong
Chinese University of Hong Kong -
P. Xepapadaki
National and Kapodistrian University of Athens -
R. Abou-Taam
Hôpital Necker Enfants Malades -
I. Agache
Universitatea Transilvania din Brasov -
J. Castro-Rodriguez
Pontificia Universidad Católica de Chile -
Z. Chen
Zhejiang University School of Medicine -
P. Cros
Hopital Morvan -
J. Dubus
Hopital La Timone -
Z. El-Sayed
Ain Shams University -
R. El-Owaidy
Ain Shams University -
W. Feleszko
Medical University of Warsaw -
V. Fierro
IRCCS Ospedale Pediatrico Bambino Gesù -
A. Fiocchi
IRCCS Ospedale Pediatrico Bambino Gesù -
L. Garcia-Marcos
Universidad de Murcia, IMIB-Arrixaca & Network of Asthma and Adverse and Allergic Reactions (ARADyAL) -
A. Goh
Rush Medical College -
E. Hossny
Ain Shams University -
Y. Huerta Villalobos
Hospital General de Mexico -
T. Jartti
Oulu University Hospital -
P. Le Roux
Groupe Hospitalier du Havre -
J. Levina
Russian Academy of Sciences -
A. López García
Allergy and Clinical Immunology Service of the University Hospital of Puebla -
Á. Ramos
Hospital Universitari i Politècnic La Fe -
M. Morais-Almeida
Hospital CUF Descobertas -
C. Murray
Faculty of Biology, Medicine and Health -
K. Nagaraju
VN Allergy & Asthma Research Centre -
M. Nagaraju
Saveetha Medical College and Hospital -
E. Navarrete Rodriguez
Hospital Infantil de Mexico Federico Gomez -
L. Namazova-Baranova
Russian Academy of Sciences, Ministry of Health of Russian Federation -
A. Nieto Garcia
Hospital Universitari i Politècnic La Fe -
C. Pozo Beltrán
Hospital with Specialties Juan María de Salvatierra, Hospital Infantil de Mexico Federico Gomez -
T. Ratchataswan
Children's Hospital Boston -
D. Rivero Yeverino
Hospital Universitario de Puebla -
E. Rodríguez Zagal
Hospital General de Mexico -
C. Schweitzer
CHU de Nancy -
M. Tulkki
Turun Yliopistollinen Keskussairaala -
K. Wasilczuk
Medical University of Warsaw -
D. Xu
Zhejiang University School of Medicine - A. Alekseeva
- B. Almeida
- M. Andre
- P. Arimova
- A. Blonde
- A. Cunningham
- S. Da Mota
- K. Efendieva
- V. Kalugina
- S. Kiefer
- A. Klein
- C. López
- J. López
- C. Moratellti
- M. Fuentes Pérez
- M. Simermann
- J. Tapia
- A. Tatopoulos
- E. Vishneva
- Κ. Volkov
- L. Bacharier
- M. Bonini
- T. Craig
- Z. Diamant
- F. Ducharme
- J. Gern
- J. Grigg
- E. Hamelmann
- G. Hedlin
- T. Jartti
- O. Kalayci
- A. Kaplan
- J. Konradsen
- P. Kuna
- S. Lau
- P. Le Souef
- R. Lemanske
- M. Makela
- P. Matricardi
- R. Gómez
- M. Miligkos
- P. Pitrez
- D. Price
- P. Pohunek
- G. Roberts
- A. Sheikh
- I. Tsiligianni
- S. Turner
- A. Valiulis
- T. Winders
- O. Yusuf
- H. Zar
Название журнала
- Allergy: European Journal of Allergy and Clinical Immunology
Финансирующая организация
- Manchester Biomedical Research Centre
Номер гранта
- undefined
Тип документа
- journal article
Тип лицензии Creative Commons
- CC BY
Правовой статус документа
- Свободная лицензия
Источник
- scopus
