SARS, SARS again, and MERS. Review of animal models of human respiratory syndromes caused by coronavirus infections

Нагорных Алексей Михайлович; Тюменцев Александр Игоревич; Тюменцева Марина Алексеевна; Акимкин Василий Геннадиевич

Статья

SARS, снова SARS и MERS. Обзор животных моделей респираторных синдромов человека, вызываемых коронавирусными инфекциями

Нагорных Алексей Михайлович,

Тюменцев Александр Игоревич,

Тюменцева Марина Алексеевна,

Акимкин Василий Геннадиевич,

2020

https://doi.org/10.36233/0372-9311-2020-97-5-6

Крупные вспышки респираторных синдромов человека, вызываемых коронавирусными инфекциями, с начала ХХI в. стали причиной гибели более миллиона человек на планете. Несмотря на то что первая волна коронавирусной инфекции случилась еще в 2002 г, до сегодняшнего дня не существует ни од¬ной адекватной животной модели, одновременно удовлетворяющей потребности научного сообщества в воспроизведении патогенеза, клинических проявлений, иммуногенности, разработке и испытании средств специфической профилактики и терапии тяжелого острого респираторного синдрома, ближневосточного респираторного синдрома и коронавирусного заболевания 2019 г. (COVID-19). Цель работы — представить актуальную информацию по известным животным моделям респираторных синдромов человека, вызываемых коронавирусными инфекциями, и акцентировать внимание читателя на их адекватности, заключающейся в максимально точной имитации клинических признаков и патоморфологических изменений.

Цитирование

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Версии

1. Version of Record от 2020-11-02

Метаданные

Об авторах

Нагорных Алексей Михайлович
ФБУН «Центральный научно-исследовательский институт эпидемиологии» Роспотребнадзора
Тюменцев Александр Игоревич
ФБУН «Центральный научно-исследовательский институт эпидемиологии» Роспотребнадзора
Тюменцева Марина Алексеевна
ФБУН «Центральный научно-исследовательский институт эпидемиологии» Роспотребнадзора
Акимкин Василий Геннадиевич
ФБУН «Центральный научно-исследовательский институт эпидемиологии» Роспотребнадзора

Предметная рубрика

COVID-19

Название журнала

Journal of microbiology, epidemiology and immunobiology

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431-444

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journal article

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CC BY

Правовой статус документа

Свободная лицензия

Источник

elpub

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Статья

SARS, снова SARS и MERS. Обзор животных моделей респираторных синдромов человека, вызываемых коронавирусными инфекциями

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