The article deals with the issue of Euroscepticism and Atlanticscepticism in France which has become extremely relevant due to the withdrawal of the UK from the EU. In 2016-2017 Frexit seemed to be a real alternative for France, as this idea was supported by Marine Le Pen, a right-wing politician, who took part in the second round of the 2017 French presidential elections. However, nowadays the most powerful French Eurosceptic politicians and parties, including Jean-Luc Mélenchon, the leader of the left-wing party Unbowed France (La France Insoumise), Marine Le Pen and her National Rally (Rassemblement national), are not campaigning for the withdrawal from the EU. On the contrary, they support the transformation of the EU based on neoliberal principles. The author pays special attention to the approaches of the French Eurosceptics highlighting the fact that the French Eurosceptics are also Atlanticsceptics. There is an objective reason for this: the European integration cannot be reshaped without a reconsideration of Euro-Atlantic cooperation. The crisis of the modern world-system accompanied by the US crisis of hegemony threatens the Washington Consensus, which has reaffirmed the commitment of different countries, including the EU-members, to the neoliberal social and economic course. Applying the world-systems analysis, the author comes to the conclusion that the concepts of alternative Europe requires Atlanticscepticism or even Anti-Atlanticism. Moreover, the current crisis opens new prospects for the French Eurosceptics who also support Atlantic Scepticism. The issue of Euroscepticism becomes even more acute in the context of the world economic crisis and coronavirus pandemic.