The coronavirus pandemic compels us to reassess the main risks the world and individual countries, including Russia, are facing, and reconsider basic principles of international cooperation in global security. Urgent concerted efforts should focus on three major tasks: ensuring global and people’s individual security; enhancing law enforcement, including anti-terrorist programs with a special emphasis placed on cybersecurity and fight against bio-hazards; and promoting robust functioning of the global economy and national economies. The pandemic has set new requirements for sectors directly influencing people’s living conditions: education, healthcare, labor, recreation, the motivation system, etc. The response to the new challenges posed by the pandemic crisis must be universal, which implies consistent full-fledged interaction between governments, institutions, and businesses. It is important to strike a balance between the interests of the state and individuals, maintain due transparency, and share information, skills and various technological solutions.