Статья

Changes in kidney function and premorbid nephrologic anamnesis in patients with COVID-19, complicated by pneumonia

E. Evsikov, I. Gordeev, V. Vechorko, O. Baikova, N. Artamonova,
2020

Coronavirus is an infection that affects not only the human immune and respiratory systems. COVID-19 has similar symptoms to that of acute respiratory infections and influenza, with complications of a new coronavirus infection affecting the heart, kidneys and other internal organs. Patients with chronic kidney disease (CKD) belong to the group of particularly high risk of COVID-19 infection and high lethality in the development of the disease. This is due to the fact that the cause of CKD is the main population diseases (diabetes mellitus, hypertension, obesity, atherosclerosis), as well as old age, which themselves contribute to high morbidity and mortality from COVID-19. Objective. To evaluate the frequency of development of renal function disorders and their semiotics in patients with COVID-19, complicated by pneumonia, who were hospitalized in the Moscow multidisciplinary hospital for diagnosis and treatment, as well as their pre-morbid background, the frequency of chronic pathology of the urinary system and disorders of carbohydrate metabo-lism and diabetes. Material and methods. The data were analyzed from 206 patients (82 men and 124 women) aged 26 to 97 years (average age 56.8±6.1 years) undergoing treatment in the 3rd department of Clinical Hospital No. 15 named after O.M. Filatov. 197 patients were discharged from the hospital, 6 patients died. CKD classifications were used from 2006 and 2013 years for division of patients into groups. There were 2 groups of patients of different ages: the 1st group — 78 patients (31 men, 47 women) aged 26—60 years (average age 48.6 years); the 2nd group — 128 patients (51 men, 77 women) aged 61—97 years (average age 74.2 years). The kidney ultrasound was performed on a Lojik-400 ultrasound scanner («General Electric», USA). In total, kidney ultrasound was carried out on 26 patients. The glomerular filtration rate (GFR) was calculated using the Cockroft-Golt formu-la, taking into account the level of creatinine concentration in blood serum, age and sex of the patient. The concentration of cre-atinine in the blood serum was determined by the method of O. Shyuk with sodium picrate on a spectrophotometer Getpremier (USA). Results. GFR was on average 23.7% higher (p

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  • 1. Version of Record от 2020-01-01

Метаданные

Об авторах
  • E. Evsikov
    City clinical hospital № 15 named after O.M. Filatov, Pirogov Russian National Research Medical University (RNRMU)
  • I. Gordeev
    Pirogov Russian National Research Medical University (RNRMU)
  • V. Vechorko
    City clinical hospital № 15 named after O.M. Filatov
  • O. Baikova
    City clinical hospital № 15 named after O.M. Filatov, Pirogov Russian National Research Medical University (RNRMU)
  • N. Artamonova
    City clinical hospital № 15 named after O.M. Filatov
Название журнала
  • Profilakticheskaya Meditsina
Том
  • 23
Выпуск
  • 7
Страницы
  • 37-42
Номер гранта
  • undefined
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus