According to the world statistics, men are much more susceptible to infection with the new coronavirus than women. Nowadays, investigation of potential impact of COVID-19 on men’s reproductive health is a particularly relevant topic. Previous research has shown that more than 25 viruses, including herpes simplex virus and human immunodeficiency virus, can infect human sperm. It is currently not fully understood whether the novel coronavirus SARS-CoV-2 has a negative impact on sperm quality and whether the virus is sexually trans-mitted. Published data indicate decreased sperm quality and possible development of orchitis in patients with COVID-19. Moreover, severe stress and corticosteroid therapy may be risk factors for patients’ sexual dysfunction. Thus, further studies are needed to determine the effects of COVID-19 on men’s reproductive health, which will help to optimize the management and rehabilitation of these patients.