This article deals with the interaction problems between man, nature and social institutions in the context of changing politics and strategy of the state in this field. Features of anthropogenic load on the agro-industrial complex were studied. The concept of barriers to entry the agri-food market, classification and types of barriers were defined. Ecological-social barriers have been investigated. The article is intended for specialists of the Ministry of agriculture and food of the Omsk oblast and local self-government bodies of regional municipalities, heads of agricultural organizations and processing enterprises, farmers, market specialists, researchers, teachers and students of agricultural universities.