Markers of Endothelial Cells in Normal and Pathological Conditions

N. Goncharov; P. Popova; P. Avdonin; I. Kudryavtsev; M. Serebryakova; E. Korf; P. Avdonin

Статья

Markers of Endothelial Cells in Normal and Pathological Conditions

N. Goncharov, P. Popova, P. Avdonin, I. Kudryavtsev, M. Serebryakova, E. Korf, P. Avdonin,

2020

https://doi.org/10.1134/S1990747819030140

Abstract: Endothelial cells (ECs) line the blood vessels and lymphatic vessels, as well as heart chambers, forming the border between the tissues, on the one hand, and blood or lymph, on the other. Such a strategic position of the endothelium determines its most important functional role in the regulation of vascular tone, hemostasis, and inflammatory processes. The damaged endothelium can be both a cause and a consequence of many diseases. The state of the endothelium is indicated by the phenotype of these cells, represented mainly by (trans)membrane markers (surface antigens). This review defines endothelial markers, provides a list of them, and considers the mechanisms of their expression and the role of the endothelium in certain pathological conditions.

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1. Version of Record от 2020-07-01

Метаданные

Об авторах

N. Goncharov
Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Research Institute of Hygiene, Occupational Pathology and Human Ecology
P. Popova
City Polyclinic no. 19
P. Avdonin
NK Koltsov Institute of Developmental Biology RAS
I. Kudryavtsev
Institute of Experimental Medicine of the North-West Branch of the Russian Academy of Medical Sciences, Far Eastern Federal University
M. Serebryakova
Institute of Experimental Medicine of the North-West Branch of the Russian Academy of Medical Sciences
E. Korf
Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences
P. Avdonin
NK Koltsov Institute of Developmental Biology RAS

Название журнала

Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology

Том

Выпуск

Страницы

167-183

Финансирующая организация

Russian Science Foundation

Номер гранта

18-15-00417

Тип документа

journal article

Тип лицензии Creative Commons

CC BY

Правовой статус документа

Свободная лицензия

Источник

scopus

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Статья

Markers of Endothelial Cells in Normal and Pathological Conditions

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