Статья

Towards effective COVID‑19 vaccines: Updates, perspectives and challenges (Review)

D. Calina, A. Docea, D. Petrakis, A. Egorov, A. Ishmukhametov, A. Gabibov, M. Shtilman, R. Kostoff, F. Carvalho, M. Vinceti, D. Spandidos, A. Tsatsakis,
2020

In the current context of the pandemic triggered by SARS-COV-2, the immunization of the population through vaccination is recognized as a public health priority. In the case of SARS‑COV‑2, the genetic sequencing was done quickly, in one month. Since then, worldwide research has focused on obtaining a vaccine. This has a major economic impact because new technological platforms and advanced genetic engineering procedures are required to obtain a COVID‑19 vaccine. The most difficult scientific challenge for this future vaccine obtained in the laboratory is the proof of clinical safety and efficacy. The biggest challenge of manufacturing is the construction and validation of production platforms capable of making the vaccine on a large scale.

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Версии

  • 1. Version of Record от 2020-07-01

Метаданные

Об авторах
  • D. Calina
    Universitatea de Medicina si Farmacie din Craiova
  • A. Docea
    Universitatea de Medicina si Farmacie din Craiova
  • D. Petrakis
    Panepistimio Kritis
  • A. Egorov
    Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences
  • A. Ishmukhametov
    Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences
  • A. Gabibov
    Russian Academy of Sciences
  • M. Shtilman
    Mendeleev University of Chemical Technology of Russia
  • R. Kostoff
    Georgia Institute of Technology
  • F. Carvalho
    Universidade do Porto
  • M. Vinceti
    Università degli Studi di Modena e Reggio Emilia
  • D. Spandidos
    Panepistimio Kritis
  • A. Tsatsakis
    Panepistimio Kritis
Название журнала
  • International journal of molecular medicine
Том
  • 46
Выпуск
  • 1
Страницы
  • 3-16
Номер гранта
  • undefined
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus