COVID-19.рф: ИНФОРМАЦИЯ ПРОТИВ ПАНДЕМИИ

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Статья

Tick-Borne Encephalitis Electrochemical Detection by Multilayer Perceptron on Liquid-Metal Interface

A. Ivanov, K. Nikolaev, A. Stekolshchikova, W. Tesfatsion, S. Yurchenko, K. Novoselov, D. Andreeva, M. Rubtsova, M. Vorovitch, A. Ishmukhametov, A. Egorov, E. Skorb,
2020
https://doi.org/10.1021/acsabm.0c00954

This work depicts an electrochemical hydrogel-eutectic gallium indium alloy interface for the detection of tick-borne encephalitis (TBE) virus. This interface allows recording of nonlinear current-voltage responses, depending on the composition of the hydrogel. The current-voltage data for the machine learning model are trained by a multilayer perceptron. This model accurately recognizes the TBE antibody, antigen, and an antibody-antigen complex in mixture with interfering bovine serum albumin with 93% accuracy. Thus, this interface can be used as a convenient method for expressed viruses and pathogens detection.

Цитирование

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Источник

Версии

  • 1. Version of Record от 2020-11-16

Метаданные

Об авторах
  • A. Ivanov
    Saint Petersburg National Research University of Information Technologies, Mechanics and Optics University ITMO
  • K. Nikolaev
    Saint Petersburg National Research University of Information Technologies, Mechanics and Optics University ITMO
  • A. Stekolshchikova
    Saint Petersburg National Research University of Information Technologies, Mechanics and Optics University ITMO
  • W. Tesfatsion
    Saint Petersburg National Research University of Information Technologies, Mechanics and Optics University ITMO
  • S. Yurchenko
    Bauman Moscow State Technical University
  • K. Novoselov
    National University of Singapore
  • D. Andreeva
    National University of Singapore
  • M. Rubtsova
    Lomonosov Moscow State University
  • M. Vorovitch
    Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Sechenov First Moscow State Medical University
  • A. Ishmukhametov
    Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Sechenov First Moscow State Medical University
  • A. Egorov
    Lomonosov Moscow State University, Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences
  • E. Skorb
    Saint Petersburg National Research University of Information Technologies, Mechanics and Optics University ITMO
Название журнала
  • ACS Applied Bio Materials
Том
  • 3
Выпуск
  • 11
Страницы
  • 7352-7356
Финансирующая организация
  • Russian Foundation for Basic Research
Номер гранта
  • 18-38-20182
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus
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