Статья

Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI

G. De Luca, M. Verdoia, M. Cercek, L. Jensen, M. Vavlukis, L. Calmac, T. Johnson, G. Ferrer, V. Ganyukov, W. Wojakowski, T. Kinnaird, C. van Birgelen, Y. Cottin, A. IJsselmuiden, B. Tuccillo, F. Versaci, K. Royaards, J. Berg, M. Laine, M. Dirksen, M. Siviglia, G. Casella, P. Kala, J. Díez Gil, A. Banning, V. Becerra, C. De Simone, A. Santucci, X. Carrillo, A. Scoccia, G. Amoroso, A. Lux, T. Kovarnik, P. Davlouros, J. Mehilli, G. Gabrielli, X. Rios, N. Bakraceski, S. Levesque, G. Cirrincione, V. Guiducci, M. Kidawa, L. Spedicato, L. Marinucci, P. Ludman, F. Zilio, G. Galasso, E. Fabris, M. Menichelli, A. Garcia-Touchard, S. Manzo, G. Caiazzo, J. Moreu, J. Forés, L. Donazzan, L. Vignali, R. Teles, E. Benit, P. Agostoni, F. Bosa Ojeda, H. Lehtola, S. Camacho-Freiere, A. Kraaijeveld, Y. Antti, M. Boccalatte, P. Deharo, I. Martínez-Luengas, B. Scheller, D. Alexopulos, R. Moreno, E. Kedhi, G. Uccello, B. Faurie, A. Gutierrez Barrios, F. Di Uccio, B. Wilbert, P. Smits, G. Cortese, G. Parodi, D. Dudek,
2020

Background: The fear of contagion during the coronavirus disease-2019 (COVID-19) pandemic may have potentially refrained patients with ST-segment elevation myocardial infarction (STEMI) from accessing the emergency system, with subsequent impact on mortality. Objectives: The ISACS-STEMI COVID-19 registry aims to estimate the true impact of the COVID-19 pandemic on the treatment and outcome of patients with STEMI treated by primary percutaneous coronary intervention (PPCI), with identification of “at-risk” patient cohorts for failure to present or delays to treatment. Methods: This retrospective registry was performed in European high-volume PPCI centers and assessed patients with STEMI treated with PPPCI in March/April 2019 and 2020. Main outcomes are the incidences of PPCI, delayed treatment, and in-hospital mortality. Results: A total of 6,609 patients underwent PPCI in 77 centers, located in 18 countries. In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio: 0.811; 95% confidence interval: 0.78 to 0.84; p < 0.0001). The heterogeneity among centers was not related to the incidence of death due to COVID-19. A significant interaction was observed for patients with arterial hypertension, who were less frequently admitted in 2020 than in 2019. Furthermore, the pandemic was associated with a significant increase in door-to-balloon and total ischemia times, which may have contributed to the higher mortality during the pandemic. Conclusions: The COVID-19 pandemic had significant impact on the treatment of patients with STEMI, with a 19% reduction in PPCI procedures, especially among patients suffering from hypertension, and a longer delay to treatment, which may have contributed to the increased mortality during the pandemic. (Primary Angioplasty for STEMI During COVID-19 Pandemic [ISACS-STEMI COVID-19] Registry; NCT04412655).

Цитирование

Похожие публикации

Документы

Источник

Версии

  • 1. Version of Record от 2020-11-17

Метаданные

Об авторах
  • G. De Luca
    Università degli Studi del Piemonte Orientale "Amedeo Avogadro"
  • M. Verdoia
    ASL 12
  • M. Cercek
    Univerzitetni Klinični Center Ljubljana
  • L. Jensen
    Odense Universitetshospital
  • M. Vavlukis
    SS Cyril and Methodius University
  • L. Calmac
    Clinical Emergency Hospital of Bucharest
  • T. Johnson
    University of Bristol
  • G. Ferrer
    Hospital Universitari de Bellvitge
  • V. Ganyukov
    Kuzbass Cardiology Center SB RAS
  • W. Wojakowski
    Slaski Uniwersytet Medyczny w Katowicach
  • T. Kinnaird
    University Hospital of Wales
  • C. van Birgelen
    Medisch Spectrum Twente (MST)
  • Y. Cottin
    Centre Hospitalier Universitaire Dijon Bourgogne
  • A. IJsselmuiden
    Amphia Hospital
  • B. Tuccillo
    Ospedale del Mare
  • F. Versaci
    Santa Maria Goretti Hospital
  • K. Royaards
    Division of Cardiology
  • J. Berg
    St. Antonius Ziekenhuis
  • M. Laine
    Helsinki University Hospital
  • M. Dirksen
    Division of Cardiology
  • M. Siviglia
    Azienda Ospedaliera Bianchi-Melacrino-Morelli
  • G. Casella
    Ospedale Maggiore
  • P. Kala
    Fakultni Nemocnice Brno
  • J. Díez Gil
    Hospital Universitari i Politècnic La Fe
  • A. Banning
    John Radcliffe Hospital
  • V. Becerra
    Hospital Universitari Virgen de la Victoria
  • C. De Simone
    Division of Cardiology
  • A. Santucci
    Azienda Ospedaliera di Perugia
  • X. Carrillo
    Hospital Universitari Germans Trias i Pujol
  • A. Scoccia
    Ospedale "Sant'Anna"
  • G. Amoroso
    Our Lady Hospital - Amsterdam
  • A. Lux
    University Hospital Maastricht
  • T. Kovarnik
    Charles University
  • P. Davlouros
    Panepistimion Patron
  • J. Mehilli
    Klinikum der Universität München
  • G. Gabrielli
    Azienda Ospedaliera Universitaria Ospedali Riuniti, Ancona
  • X. Rios
    Universidade da Coruña
  • N. Bakraceski
    Center for Cardiovascular Diseases
  • S. Levesque
    Centre Hospitalier Universitaire de Poitiers
  • G. Cirrincione
    ARNAS Ospedale Civico
  • V. Guiducci
    IRCCS Azienda Unità Sanitaria Locale di Reggio Emilia
  • M. Kidawa
    Medical University of Lodz
  • L. Spedicato
    Ospedale Santa Maria della Misericordia, Udine
  • L. Marinucci
    Azienda Ospedaliera "Ospedali Riuniti Marche Nord"
  • P. Ludman
    University Hospitals Birmingham NHS Foundation Trust
  • F. Zilio
    Ospedale S. Chiara
  • G. Galasso
    Ospedale San Giovanni di Dio e Ruggi D'Aragona
  • E. Fabris
    Azienda Sanitaria Universitaria Integrata di Trieste
  • M. Menichelli
    “F. Spaziani” Hospital
  • A. Garcia-Touchard
    Hospital Universitario Puerta de Hierro
  • S. Manzo
    Hôpital Lariboisiere AP-HP
  • G. Caiazzo
    Ospedale “G Moscati”
  • J. Moreu
    Complejo Hospitalario de Toledo
  • J. Forés
    Hospital Clinico Universitario de Valencia
  • L. Donazzan
    Ospedale ”S. Maurizio” Bolzano Ospedale ”S. Maurizio” Bolzano
  • L. Vignali
    Azienda Ospedaliera
  • R. Teles
    Hospital de Santa Cruz, Carnaxide
  • E. Benit
    Division of Cardiology
  • P. Agostoni
    ZiekenhuisNetwerk Antwerpen
  • F. Bosa Ojeda
    Hospital Universitario de Canarias
  • H. Lehtola
    Oulu University Hospital
  • S. Camacho-Freiere
    Juan Ramón Jiménez Hospital
  • A. Kraaijeveld
    University Medical Center Utrecht
  • Y. Antti
    Turun Yliopistollinen Keskussairaala
  • M. Boccalatte
    Santa Maria delle Grazie Hospital
  • P. Deharo
    Aix Marseille Université
  • I. Martínez-Luengas
    Hospital de Cabuenes
  • B. Scheller
    Universitätsklinikum des Saarlandes Medizinische Fakultät der Universität des Saarlandes
  • D. Alexopulos
    Attikon University Hospital
  • R. Moreno
    Hospital Universitario La Paz
  • E. Kedhi
    General Hospital St. Jan
  • G. Uccello
    Azienda Ospedaliera Ospedale Di Lecco
  • B. Faurie
    Groupe Hospitalier Mutualiste de Grenoble
  • A. Gutierrez Barrios
    Hospital Universitario Puerta del Mar
  • F. Di Uccio
    Ospedale del Mare
  • B. Wilbert
    St. Antonius Ziekenhuis
  • P. Smits
    Division of Cardiology
  • G. Cortese
    Università degli Studi di Padova
  • G. Parodi
    Azienda Ospedaliero Universitaria Sassari
  • D. Dudek
    Uniwersytet Jagielloński Collegium Medicum
Название журнала
  • Journal of the American College of Cardiology
Том
  • 76
Выпуск
  • 20
Страницы
  • 2321-2330
Финансирующая организация
  • Università degli Studi del Piemonte Orientale
Номер гранта
  • 20178S4EK9
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus