Статья

Lithium chloride for the novel coronavirus infection covid-19

O. Grebenchikov, A. Kuzovlev, A. Baeva,
2020

The novel coronavirus infection COVID-19 is associated with increased release of inflammatory cytokines (cytokine storm) and reactive oxygen species. These processes result a damage to the endothelium, pulmonary alveolar epithelium and their basal membranes (including the structures of blood-air barrier), increased vascular permeability and non-cardiogenic pulmonary edema. These mechanisms underlie the pathogenesis of acute respiratory distress syndrome in patients with coronavirus infection COVID-19. In this review, we have analyzed the data on the effect of lithium chloride on cytokine storm, increased vascular endothelial permeabili-ty, apoptosis of endotheliocyte and advanced activation of innate immune cells in patients with coronavirus infection COVID-19.

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Версии

  • 1. Version of Record от 2020-12-01

Метаданные

Об авторах
  • O. Grebenchikov
    Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
  • A. Kuzovlev
    Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
  • A. Baeva
    Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
Название журнала
  • Russian Journal of Anesthesiology and Reanimatology
Том
  • 6
Выпуск
  • 2
Страницы
  • 40-44
Номер гранта
  • undefined
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC BY
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus