Objective. To study the parameters of the hormonal status, hemostasis parameters, biochemical blood test and semen analysis in men of reproductive age who have undergone a new coronavirus infection (COVID-19). Material and methods. The study included 50 men who had a new coronavirus infection (COVID-19) and received treatment in hospital setting. The study was conducted 3 months later in the presence of positive IgG antibodies to COVID-19. All patients underwent a comprehensive examination, including the study of the hormonal profile, hemostasis parameters, biochemical blood test, identification of concomitant urological diseases, as well as semen analysis (concentration, mobility, morphology, MAR-test), according to WHO 2010 criteria. Results. The examination revealed a decrease in the level of total testosterone in 19 (38%) patients. The values ranged from 6.41 to 10 nmol/l (reference values 10.50—35.40 nmol/l). The biochemical blood analysis revealed the following changes: an increase in creatinine levels to 117—180 μM / L (reference values 80—115 μM/L) in 15 (30%) patients, total bilirubin (22—42.7 μM/L (refer-ence values 1.7—21.0 μMol/L) in 9 (18%) patients, alanine aminotransferase 43-109 U/L (reference values 0.0—41 U/L) in 19 (38%) patients, the level of aspartate aminotransferase was 45—82 U/L (with a norm of 0.0—40 U/L) in 10 (20%) patients Analysis of the hemo-stasis revealed hypercoagulation in 11 (22%) patients, and hypocoagulation in 6 (12%) patients. Abnormalities in the semen analysis were found in 10 (20%) patients with teratozoospermia in all the samples. In 8 (16%) patients, leukospermia was determined. There was a statistically significant decrease in the serum total testosterone level in 38% of patients (p