Objective – identify the relationship between the phenomena of uncertainty tolerance and hardiness in adolescents. Uncertainty tolerance (UT) is understood as a personality trait that manifests itself in an ability to accept uncertainty and act confidently in unstable situations. Adolescence is characterized as a period of instability. It is thus assumed that uncertainty tolerance is a significant parameter in the structure of adolescents’ hardiness. The research was designed to identify the relationship between uncertainty tolerance and hardiness in adolescents using Spearman’s rank correlation coefficient. Survey respondents: 66 schoolchildren in grades 9 and 11 (15–18 years old), of which 34 are boys and 32 are girls. For the research, a set of methods was used. Hardiness Survey (S. Maddi adapted by D. A. Leont’ev); McLane’s Multiple Stimulus Types Ambiguity Tolerance Scale-I ((MSTAT-I) adapted by E. G. Lukovitskaia); Adaptive behavioural strategies Questionnaire (adolescent form: ASP-1) by N. N. Mel’nikova. The results of the research indicate that the relationship between uncertainty tolerance to and the scales (p ≤ 0.0001) of Risk Acceptance (r = 0.75), Control (r = 0.71), Engagement (r = 0.65), Vitality (r = 0.65) has been determined. Empirical data contribute to the understanding of uncertainty tolerance as a basic personality trait that contributes to the effective organization of life with a limited amount of information about future events. Building hardiness enables adolescents to cope with age-related challenges in a more efficient way.