Статья

Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection

H. Simon, A. Karaulov, M. Bachmann,
2021

A vaccine to protect against COVID-19 is urgently needed. Such a vaccine should efficiently induce high-affinity neutralizing antibodies which neutralize SARS-CoV-2, the cause of COVID-19. However, there is a concern regarding both vaccine-induced eosinophilic lung disease and eosinophil-associated Th2 immunopotentiation following infection after vaccination. Here, we review the anticipated characteristics of a COVID-19 vaccine to avoid vaccine-associated eosinophil immunopathology. © 2020

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Версии

  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • H. Simon
    Institute of Pharmacology, University of Bern, Bern, Switzerland
  • A. Karaulov
    Department of Clinical Immunology and Allergology, Sechenov University, Moscow, Russian Federation
  • M. Bachmann
    Department of Rheumatology, Immunology and Allergology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Название журнала
  • International Archives of Allergy and Immunology
Том
  • 181
Выпуск
  • 8
Страницы
  • 624-628
Ключевые слова
  • Fc receptor; immunoglobulin G antibody; immunoglobulin G1; immunoglobulin G3; neutralizing antibody; SARS-CoV-2 vaccine; toll like receptor affecting agent; COVID-19 vaccine; neutralizing antibody; virus vaccine; antibody production; cellular immunity; coronavirus disease 2019; eosinophil; eosinophilia; human; immune response; immunopathology; Loeffler pneumonia; lung infection; lymphocytic infiltration; mucosal immunity; nonhuman; priority journal; reinfection; Review; Severe acute respiratory syndrome coronavirus 2; vaccination; virus load; virus particle; adverse event; Betacoronavirus; biosynthesis; Coronavirus infection; immunology; pandemic; physiology; Th2 cell; vaccination; virus pneumonia; Antibodies, Neutralizing; Betacoronavirus; Coronavirus Infections; Eosinophils; Humans; Pandemics; Pneumonia, Viral; Th2 Cells; Vaccination; Viral Vaccines
Издатель
  • S. Karger AG
Тип документа
  • Review
Источник
  • scopus