Статья

Lethal outcomes in influenza: Clinic-pathological approach to immediate death causes

A. Yakovlev, V. Zinserling, E. Esaulenko,
2021

Influenza is one of the most outspread infections not seldom leading to lethal outcomes. Immediate death causes are analyzed rarely. Material and methods. We provided clinic-pathological correlations in 23 cases with lethal outcomes in 1999, 15-in 2009, 31 in 2016 and 10 in 2017. Results. It was shown that in 2009 and 2017 most frequent lethal outcomes were related to bacterial superinfection in elderly people with severe background pathology. In 2009 and 2016 the leading role played respiratory distress syndrome predominantly in people of middle age, frequently with obesity. Conclusions: by circulation of different strains of influenza A virus the disease has substantial peculiarities. Lethal outcomes may be related: 1) severe respiratory insufficiency due to respiratory distress syndrome; 2) generalized viral infection; 3) secondary bacterial pneumonia; 4) aggravation of severe somatic diseases. Many aspects of pathogenesis need complex.study.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • A. Yakovlev
    Saint-Petersburg State University, Saint-Petersburg, Russian Federation
  • V. Zinserling
    Clinical Infectious Hospital, S.P. Botkin, Saint-Petersburg, Russian Federation
  • E. Esaulenko
    National Medical Research Center, V.A. Almazov, Saint-Petersburg, Russian Federation
Название журнала
  • Jurnal Infektologii
Том
  • 9
Выпуск
  • 4
Страницы
  • 53-58
Издатель
  • Interregional public organization Association of infectious disease specialists of Saint-Petersburg and Leningrad region (IPO AIDSSPbR)
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus