Influenza burden, prevention, and treatment in asthma-A scoping review by the EAACI Influenza in asthma task force

J. Schwarze; P. Openshaw; A. Jha; G. del; D. Firinu; O. Tsilochristou; G. Roberts; A. Selby; C. Akdis; I. Agache; A. Custovic; E. Heffler; G. Pinna; M. Khaitov; A. Nikonova; N. Papadopoulos; A. Akhlaq; U. Nurmatov; H. Renz; A. Sheikh; C. Skevaki

Статья

Influenza burden, prevention, and treatment in asthma-A scoping review by the EAACI Influenza in asthma task force

J. Schwarze, P. Openshaw, A. Jha, G. del, D. Firinu, O. Tsilochristou, G. Roberts, A. Selby, C. Akdis, I. Agache, A. Custovic, E. Heffler, G. Pinna, M. Khaitov, A. Nikonova, N. Papadopoulos, A. Akhlaq, U. Nurmatov, H. Renz, A. Sheikh, C. Skevaki,

2021

https://doi.org/10.1111/all.13333

To address uncertainties in the prevention and management of influenza in people with asthma, we performed a scoping review of the published literature on influenza burden; current vaccine recommendations; vaccination coverage; immunogenicity, efficacy, effectiveness, and safety of influenza vaccines; and the benefits of antiviral drugs in people with asthma. We found significant variation in the reported rates of influenza detection in individuals with acute asthma exacerbations making it unclear to what degree influenza causes exacerbations of underlying asthma. The strongest evidence of an association was seen in studies of children. Countries in the European Union currently recommend influenza vaccination of adults with asthma; however, coverage varied between regions. Coverage was lower among children with asthma. Limited data suggest that good seroprotection and seroconversion can be achieved in both children and adults with asthma and that vaccination confers a degree of protection against influenza illness and asthma-related morbidity to children with asthma. There were insufficient data to determine efficacy in adults. Overall, influenza vaccines appeared to be safe for people with asthma. We identify knowledge gaps and make recommendations on future research needs in relation to influenza in patients with asthma. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

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1. Version of Record от 2021-04-27

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Об авторах

J. Schwarze
Centre for Inflammation Research, The Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
P. Openshaw
Respiratory Sciences, National Heart and Lung Institute, Imperial College London, London, United Kingdom
A. Jha
Department of Medical Sciences and Public Health “M. Aresu”, University of Cagliari, Cagliari, Italy
G. del
Department of Pediatric Allergology, King's College, London, United Kingdom
D. Firinu
Faculty of Medicine, Southampton and David Hide Asthma and Allergy Centre, St Mary's Hospital, University of Southampton, Newport, Isle of Wight, United Kingdom
O. Tsilochristou
Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
G. Roberts
Department of Allergy and Clinical Immunology, Faculty of Medicine, Transylvania University Brasov, Brasov, Romania
A. Selby
Department of Paediatrics, Imperial College London, London, United Kingdom
C. Akdis
Personalized Medicine, Asthma and Allergy Clinic, Department of Biomedical Sciences, Humanitas University, Milan, Italy
I. Agache
Department of Medical Microbiology, National Kapodistrian University of Athens, Athens, Greece
A. Custovic
National Research Center Institute of Immunology of Federal Medicobiological Agency, Moscow, Russian Federation
E. Heffler
Division of Infection, Inflammation & Respiratory Medicine, The University of Manchester, Manchester, United Kingdom
G. Pinna
Allergy Department, 2nd Paediatric Clinic, National Kapodistrian University of Athens, Athens, Greece
M. Khaitov
Department of Health and Hospital Management, Institute of Business Management, Korangi Creek, Karachi, 75190, Pakistan
A. Nikonova
Division of Population Medicine, School of Medicine, Cardiff University, The National Centre for Population Health and Wellbeing Research, United Kingdom
N. Papadopoulos
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, University Hospital Giessen & Marburg, Marburg, Germany
A. Akhlaq
Asthma UK Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, United Kingdom
U. Nurmatov
H. Renz
A. Sheikh
C. Skevaki

Название журнала

Allergy: European Journal of Allergy and Clinical Immunology

Том

Выпуск

Страницы

1151-1181

Ключевые слова

influenza vaccine; antivirus agent; influenza vaccine; antiviral therapy; asthma; disease exacerbation; drug efficacy; drug safety; global disease burden; health care utilization; human; immunogenicity; influenza; influenza vaccination; morbidity; priority journal; prophylaxis; Review; seroconversion; virus load; asthma; complication; cost of illness; global health; health survey; immunology; influenza; meta analysis; outcome assessment; treatment outcome; vaccination; vaccine immunogenicity; Antiviral Agents; Asthma; Cost of Illness; Global Health; Humans; Immunogenicity, Vaccine; Influenza Vaccines; Influenza, Human; Patient Outcome Assessment; Public Health Surveillance; Treatment Outcome; Vaccination

Издатель

Blackwell Publishing Ltd

Тип документа

Review

Тип лицензии Creative Commons

Правовой статус документа

Свободная лицензия

Источник

scopus

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Статья

Influenza burden, prevention, and treatment in asthma-A scoping review by the EAACI Influenza in asthma task force

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