Статья

Novel reassortant of H1N1 swine influenza virus detected in pig population in Russia

I. Sobolev, O. Kurskaya, S. Leonov, M. Kabilov, T. Alikina, A. Alekseev, Y. Yushkov, T. Saito, Y. Uchida, J. Mine, A. Shestopalov, K. Sharshov,
2021

Pigs play an important role in interspecies transmission of the influenza virus, particularly as “mixing vessels” for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. There was a 10% identity difference between the HA and NA nucleotide sequences of isolated strains and the most phylogenetically related sequences (human influenza viruses of 1980s). Simultaneously, genome segments encoding internal proteins were found to be phylogenetically related to the A/H1N1pdm09 influenza virus. In addition, two amino acids (129–130) were deleted in the HA of A/swine/Siberia/4sw/2017 compared to that of A/swine/Siberia/1sw/2016 HA. © 2019, © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • I. Sobolev
    Department of Experimental Modeling and Pathogenesis of Infectious Diseases, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russian Federation
  • O. Kurskaya
    Siberian Federal Scientific Centre of Agro- BioTechnologies, Krasnoobsk, Russian Federation
  • S. Leonov
    Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russian Federation
  • M. Kabilov
    Division of Transboundary Animal Disease, National Institute of Animal Health, Tsukuba, Japan
  • T. Alikina
  • A. Alekseev
  • Y. Yushkov
  • T. Saito
  • Y. Uchida
  • J. Mine
  • A. Shestopalov
  • K. Sharshov
Название журнала
  • Emerging Microbes and Infections
Том
  • 8
Выпуск
  • 1
Страницы
  • 1456-1464
Ключевые слова
  • swine influenza vaccine; virus antibody; virus glycoprotein; Actinobacillus pleuropneumoniae; amino acid sequence; amino acid substitution; animal cell; animal experiment; animal model; animal tissue; antigenicity; Article; controlled study; cross reaction; experimental infection; genetic reassortment; Influenza A virus (H1N1); MDCK cell line; mouse; nonhuman; nucleotide sequence; pandemic influenza; phylogenetic tree; porcine pleuropneumonia; priority journal; Russian Federation; Sanger sequencing; swine influenza; swine influenza virus; virus detection; virus genome; virus isolation; virus replication; virus strain; virus titration; animal; classification; genetic reassortment; genetics; Influenza A virus (H1N1); isolation and purification; microbiology; orthomyxovirus infection; phylogeny; pig; swine disease; veterinary medicine; virology; Animals; Genome, Viral; Influenza A Virus, H1N1 Subtype; Orthomyxoviridae Infections; Phylogeny; Reassortant Viruses; Russia; Swine; Swine Diseases
Издатель
  • Taylor and Francis Ltd.
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus