Статья

The effect of a lipopolysaccharide from rhodobacter capsulatus PG on inflammation caused by various influenza strains

S. Zubova, M. Vorovich, A. Gambaryan, A. Ishmukhametov, S. Grachev, I. Prokhorenko,
2021

The development of a specific inflammation in mice that had been infected by two influenza virus strains, A/chicken/Kurgan/5/2005 (H5N1) and A/Hamburg/2009 MA (H1N1), was studied. We investigated the effect of a non-toxic lipopolysaccharide from Rhodobacter capsulatus PG on the survival and body weight of the mice, production of IgG antibodies, and the induction of proand anti-inflammatory cytokines in blood serum. The administration of the R. capsulatus PG lipopolysaccharide was shown to induce interferon-â synthesis, both in healthy and influenza A virus-infected mice, and to promote production of antiviral antibodies in the blood of the influenza-infected animals. © 2019 National Research University Higher School of Economics.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • S. Zubova
    Institute of Basic Biological Problems of RAS, FRC PSCBR RAS, Science Ave. 3, Pushchino, Moscow, 142290, Russian Federation
  • M. Vorovich
    FGBNU Federal Scientific Center of Research and Development of Immunobiological Preparations named M.P. Chumakov of RAS, Institute of Poliomyelitis, Kievskoye Highway, 27th km, 8/1, Moscow Region, 142782, Russian Federation
  • A. Gambaryan
    GAOUVO First Moscow State Medical University named I.M. Sechenov of Russia Health Ministry, Trubetskaya Str. 8, Moscow, 119811, Russian Federation
  • A. Ishmukhametov
  • S. Grachev
  • I. Prokhorenko
Название журнала
  • Acta Naturae
Том
  • 11
Выпуск
  • 3
Страницы
  • 46-55
Издатель
  • Acta Naturae
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus