Статья

On the unpredictability of outcomes of immunotherapy and preventive immunization against covid-19 [О НЕПРЕДСКАЗУЕМОСТИ РЕЗУЛЬТАТОВ ИММУНОТЕРАПИИ И ИММУНОПРОФИЛАКТИКИ COVID-19]

I. Chebotar, D. Shagin,
2021

This article analyzes the possibility of employing immunotherapy and preventive immunization to fight COVID-19. The authors think that treatment and prevention of the infection with anti-SARS-CoV-2 antibodies can have unpredictable outcomes. Although these antibodies can neutralize virus antigens (S-proteins), they also have the ability to enhance virus entry into the host cell. The article emphasizes the importance of solid evidence of efficacy and safety for candidate anti-COVID-19 therapies and protective measures. © 2020 Pirogov Russian National Research Medical University. All rights reserved.

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Источник

Версии

  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • I. Chebotar
    Pirogov Russian National Research Medical University, Moscow Pirogov Russian National Research Medical University, Moscow, Russian Federation
  • D. Shagin
Название журнала
  • Bulletin of Russian State Medical University
Выпуск
  • 2
Страницы
  • 13-15
Ключевые слова
  • virus antigen; virus vaccine; vitronectin; antibody dependent enhancement; Article; coronavirus disease 2019; drug efficacy; drug safety; host cell; human; immunocompetent cell; immunotherapy; nonhuman; outcome assessment; protein interaction; Severe acute respiratory syndrome coronavirus 2; vaccination; virion; virus entry
Издатель
  • Pirogov Russian National Research Medical University
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus