Статья

ARDD 2020: from aging mechanisms to interventions

G. Mkrtchyan, K. Abdelmohsen, P. Andreux, I. Bagdonaite, N. Barzilai, S. Brunak, F. Cabreiro, R. Cabo, J. Campisi, A. Cuervo, M. Demaria, C. Ewald, E. Fang, R. Faragher, L. Ferrucci, A. Freund, C. Silva-García, A. Georgievskaya, V. Gladyshev, D. Glass, V. Gorbunova, A. Grey, W. He, J. Hoeijmakers, E. Hoffmann, S. Horvath, R. Houtkooper, M. Jensen, M. Jensen, A. Kane, M. Kassem, P. Keizer, B. Kennedy, G. Karsenty, D. Lamming, K. Lee, N. MacAulay, P. Mamoshina, J. Mellon, M. Molenaars, A. Moskalev, A. Mund, L. Niedernhofer, B. Osborne, H. Pak, A. Parkhitko, N. Raimundo, T. Rando, L. Rasmussen, C. Reis, C. Riedel, A. Franco-Romero, B. Schumacher, D. Sinclair, Y. Suh, P. Taub, D. Toiber, J. Treebak, D. Valenzano, E. Verdin, J. Vijg, S. Young, L. Zhang, D. Bakula, A. Zhavoronkov, M. Scheibye-Knudsen,
2021

Aging is emerging as a druggable target with growing interest from academia, industry and investors. New technologies such as artificial intelligence and advanced screening techniques, as well as a strong influence from the industry sector may lead to novel discoveries to treat age-related diseases. The present review summarizes presentations from the 7th Annual Aging Research and Drug Discovery (ARDD) meeting, held online on the 1st to 4th of September 2020. The meeting covered topics related to new methodologies to study aging, knowledge about basic mechanisms of longevity, latest interventional strategies to target the aging process as well as discussions about the impact of aging research on society and economy. More than 2000 participants and 65 speakers joined the meeting and we already look forward to an even larger meeting next year. Please mark your calendars for the 8th ARDD meeting that is scheduled for the 31st of August to 3rd of September, 2021, at Columbia University, USA. © 2020. Mkrtchyan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. All Rights Reserved.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • G. Mkrtchyan
    Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
  • K. Abdelmohsen
    Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States
  • P. Andreux
    Amazentis SA, EPFL Innovation Park, Bâtiment C, Lausanne, Switzerland
  • I. Bagdonaite
    Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
  • N. Barzilai
    Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, United States
  • S. Brunak
    Institute for Aging Research, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, United States
  • F. Cabreiro
    Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark
  • R. Cabo
    Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, United Kingdom
  • J. Campisi
    Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, United States
  • A. Cuervo
    Buck Institute for Research on Aging, Novato, CA 94945, United States
  • M. Demaria
    Department of Developmental and Molecular Biology, Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, NY 10461, United States
  • C. Ewald
    European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, Netherlands
  • E. Fang
    Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute for Technology Zürich, Switzerland
  • R. Faragher
    Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
  • L. Ferrucci
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, United Kingdom
  • A. Freund
    Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, United States
  • C. Silva-García
    Calico Life Sciences, LLC, South San Francisco, CA 94080, United States
  • A. Georgievskaya
    Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA 02115, United States
  • V. Gladyshev
    HautAI OÜ, Tallinn, Estonia
  • D. Glass
    Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States
  • V. Gorbunova
    Regeneron Pharmaceuticals Inc., TarrytownNY 10591, United States
  • A. Grey
    Departments of Biology and Medicine, University of Rochester, Rochester, NY 14627, United States
  • W. He
    SENS Research Foundation, Mountain View, CA 94041, United States
  • J. Hoeijmakers
    Human Longevity Inc., San Diego, CA 92121, United States
  • E. Hoffmann
    Department of Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands
  • S. Horvath
    DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
  • R. Houtkooper
    Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, United States
  • M. Jensen
    Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
  • M. Jensen
    Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
  • A. Kane
    Gordian Biotechnology, San Francisco, CA 94107, United States
  • M. Kassem
    Blavatnik Institute, Department of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, MA 02115, United States
  • P. Keizer
    Molecular Endocrinology Unit, Department of Endocrinology, University Hospital of Odense and University of Southern Denmark, Odense, Denmark
  • B. Kennedy
    Department of Molecular Cancer Research, Center for Molecular Medicine, Division of Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
  • G. Karsenty
    Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University Singapore, Singapore
  • D. Lamming
    Centre for Healthy Ageing, National University Healthy System, Singapore
  • K. Lee
    Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, United States
  • N. MacAulay
    Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53792, United States
  • P. Mamoshina
    Sinovation Ventures and Sinovation AI Institute, Beijing, China
  • J. Mellon
    Department of Neuroscience, University of Copenhagen, Denmark
  • M. Molenaars
    Deep Longevity Inc., Hong Kong Science and Technology Park, Hong Kong
  • A. Moskalev
    Juvenescence Limited, Douglas, Isle of Man, United Kingdom
  • A. Mund
    Institute of Biology of FRC Komi Science Center of Ural Division of RA, Syktyvkar, Russian Federation
  • L. Niedernhofer
    Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, United States
  • B. Osborne
    University of Pittsburgh, Pittsburgh, PA 15260, United States
  • H. Pak
    Institute of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany
  • A. Parkhitko
    Department of Neurology and Neurological Sciences and Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, United States
  • N. Raimundo
    OneSkin Inc., San Francisco, CA 94107, United States
  • T. Rando
    Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden
  • L. Rasmussen
    Department of Biomedical Sciences, University of Padova, Italy
  • C. Reis
    Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany
  • C. Riedel
    Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, NSW, Australia
  • A. Franco-Romero
    Departments of Obstetrics and Gynecology, Genetics and Development, Columbia University, New York, NY 10027, United States
  • B. Schumacher
    Division of Cardiovascular Medicine, University of California, San Diego, CA 92093, United States
  • D. Sinclair
    Department of Life Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
  • Y. Suh
    Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark
  • P. Taub
    Max Planck Institute for Biology of Ageing, Cologne, Germany
  • D. Toiber
    Longevity Vision Fund, New York, NY 10022, United States
  • J. Treebak
    Insilico Medicine, Hong Kong Science and Technology Park, Hong Kong
  • D. Valenzano
  • E. Verdin
  • J. Vijg
  • S. Young
  • L. Zhang
  • D. Bakula
  • A. Zhavoronkov
  • M. Scheibye-Knudsen
Название журнала
  • Aging
Том
  • 12
Выпуск
  • 24
Страницы
  • 24486-24503
Издатель
  • Impact Journals LLC
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus