Статья

Hyperbolic rules of the cooperative organization of eukaryotic and prokaryotic genomes

S. Petoukhov,
2021

The author's method of oligomer sums for analysis of oligomer compositions of eukaryotic and prokaryotic genomes is described. The use of this method revealed the existence of general rules for the cooperative oligomeric organization of a wide list of genomes. These rules are called hyperbolic because they are associated with hyperbolic sequences including the harmonic progression 1, 1/2, 1/3, ., 1/n. These rules are demonstrated by examples of quantitative analysis of many genomes from the human genome to the genomes of archaea and bacteria. The hyperbolic (harmonic) rules, speaking about the existence of algebraic invariants in full genomic sequences, are considered as candidates for the role of universal rules for the cooperative organization of genomes. The results concerns additionally the problem of the origin of life. The described phenomenological results were obtained as consequences of the previously published author's quantum-information model of long DNA sequences. The oligomer sums method was also applied to the analysis of long genes and viruses including the COVID-19 virus; this revealed, in characteristics of many of them, the phenomenon of such rhythmically repeating deviations from model hyperbolic sequences, which are associated with DNA triplets. In addition, an application of the oligomer sums method is shown to the analysis of amino acid sequences in long proteins like the protein Titin. The topics of the algebraic harmony in living bodies and of the quantum-information approach in biology are discussed. © 2020 Elsevier B.V.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • S. Petoukhov
    Mechanical Engineering Research Institute of Russian Academy of Sciences. Russia, M. Kharitonievskiy Pereulok, 4, Moscow, 101990, Russian Federation
Название журнала
  • BioSystems
Том
  • 198
Страницы
  • -
Ключевые слова
  • connectin; DNA; oligomer; amino acid; cooperative behavior; DNA; eukaryote; genome; prokaryote; protein; quantitative analysis; viral disease; archaeal genome; Article; bacterial genome; chromosome; Drosophila melanogaster; eukaryote; genome analysis; human; human genome; insect genome; microbial genome; nonhuman; prokaryote; quantum mechanics; Severe acute respiratory syndrome coronavirus 2; virus genome; eukaryote; eukaryotic cell; genetics; genome; genomics; physiology; procedures; prokaryotic cell; Eukaryota; Prokaryota; Eukaryota; Eukaryotic Cells; Genome; Genomics; Prokaryotic Cells; SARS-CoV-2
Издатель
  • Elsevier Ireland Ltd
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus